| 1 |
34896433 | Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter. | 2022 Jan 1 |
1 |
| 2 |
32104283 | Raised CD40L expression attenuates drug resistance in Adriamycin-resistant THP-1 cells. | 2020 Mar |
1 |
| 3 |
30925062 | Identification of Thienopyrimidine Scaffold as an Inhibitor of the ABC Transport Protein ABCC1 (MRP1) and Related Transporters Using a Combined Virtual Screening Approach. | 2019 May 9 |
2 |
| 4 |
31039321 | Confirmation of Selected Synergistic Cancer Drug Combinations Identified in an HTS Campaign and Exploration of Drug Efflux Transporter Contributions to the Mode of Synergy. | 2019 Jul |
1 |
| 5 |
29016119 | 9-Deazapurines as Broad-Spectrum Inhibitors of the ABC Transport Proteins P-Glycoprotein, Multidrug Resistance-Associated Protein 1, and Breast Cancer Resistance Protein. | 2017 Nov 9 |
3 |
| 6 |
26300056 | Dinaciclib, a cyclin-dependent kinase inhibitor, is a substrate of human ABCB1 and ABCG2 and an inhibitor of human ABCC1 in vitro. | 2015 Dec 1 |
1 |
| 7 |
21968975 | Infection of H69AR cells with retroviral particles harboring interfering RNAi significantly reduced the multidrug resistance of these small cell lung cancer cells. | 2011 |
1 |
| 8 |
18924151 | The pH sensitive probe 5-(and-6)-carboxyl seminaphthorhodafluor is a substrate for the multidrug resistance-related protein MRP1. | 2009 Jan 1 |
1 |
| 9 |
19214144 | Characterization and analyses of multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphisms in Chinese population. | 2009 Mar |
1 |
| 10 |
16830181 | Heterologous expression of a mammalian ABC transporter in plant and its application to phytoremediation. | 2006 Jun |
1 |
| 11 |
15644429 | Trimers of N-alkylglycines are potent modulators of the multidrug resistance phenotype. | 2005 Apr |
1 |
| 12 |
16117892 | [Reversal of multidrug resistance of HL-60 adriamycin resistant leukemia cell line by quercetin and its mechanisms]. | 2005 Jun |
1 |
| 13 |
14757231 | Fluorescent modified phosphatidylcholine floppase activity of reconstituted multidrug resistance-associated protein MRP1. | 2004 Jan 28 |
1 |
| 14 |
15041471 | Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1). | 2004 Apr 15 |
4 |
| 15 |
15161039 | New silicon compounds as resistance modifiers against multidrug-resistant cancer cells. | 2004 Mar-Apr |
1 |
| 16 |
15498506 | Relation between the ability of some compounds to modulate the MRP1-mediated efflux of glutathione and to inhibit the MRPl-mediated efflux of daunorubicin. | 2004 Dec 1 |
1 |
| 17 |
12706238 | Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier. | 2003 May 9 |
1 |
| 18 |
12115804 | Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin. | 2002 Aug |
1 |
| 19 |
12425469 | Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine. | 2002 Oct |
2 |
| 20 |
11278000 | Nucleotide-induced conformational changes in the human multidrug resistance protein MRP1 are related to the capacity of chemotherapeutic drugs to accumulate or not in resistant cells. | 2001 Mar 23 |
1 |
| 21 |
11408043 | Kinetics of glutathione and daunorubicin efflux from multidrug resistance protein overexpressing small-cell lung cancer cells. | 2001 Jun 1 |
4 |
| 22 |
11585053 | The absence of stereoselective P-glycoprotein- and multidrug resistance-associated protein-mediated transport of daunorubicin. | 2001 Sep 1 |
1 |
| 23 |
10729360 | Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P. | 2000 Mar 17 |
2 |
| 24 |
10783828 | Diverse effects of P-glycoprotein inhibitory agents on human leukemia cells expressing the multidrug resistance protein (MRP). | 2000 Apr |
1 |
| 25 |
10969785 | Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities. | 2000 Aug 15 |
1 |
| 26 |
10188979 | ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1. | 1999 Feb |
5 |
| 27 |
10419897 | Simultaneous activity of MRP1 and Pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia. | 1999 Aug 1 |
1 |
| 28 |
10482990 | Idarubicin DNA intercalation is reduced by MRP1 and not Pgp. | 1999 Sep |
1 |
| 29 |
10565860 | Glutathione peptidomimetic drug modulator of multidrug resistance-associated protein. | 1999 Dec |
1 |
| 30 |
9443942 | Kinetics of anthracycline efflux from multidrug resistance protein-expressing cancer cells compared with P-glycoprotein-expressing cancer cells. | 1998 Jan |
4 |
| 31 |
9647783 | Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump. | 1998 Jun 29 |
8 |
| 32 |
9188796 | Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport. | 1997 May 22 |
1 |
| 33 |
9281595 | Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. | 1997 Sep |
1 |
| 34 |
8616077 | Levels of mdr1 and mrp mRNA in leukaemic cell populations from patients with acute myelocytic leukaemia are heterogenous and inversely correlated to cellular daunorubicin accumulation. | 1996 Mar |
1 |
| 35 |
8621644 | ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids. | 1996 Apr 19 |
1 |
| 36 |
8636432 | Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. | 1996 Mar 1 |
1 |
| 37 |
8909298 | ATP-dependent transport of lipophilic cytotoxic drugs by membrane vesicles prepared from MRP-overexpressing HL60/ADR cells. | 1996 Nov 5 |
1 |
| 38 |
8913319 | Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukaemia cells. | 1996 Aug |
2 |
| 39 |
7628644 | ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): no inhibition by intracellular glutathione depletion. | 1995 Jul 17 |
2 |
| 40 |
7916458 | The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. | 1994 Sep 13 |
3 |
| 41 |
7945406 | Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells. | 1994 Sep 15 |
1 |