benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone

caspase 8 ; Homo sapiens







162 Article(s)
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1 35522455 A new photodynamic therapy photosensitizer (p1) promotes apoptosis of keloid fibroblasts by targeting caspase-8. 2022 May 6 1
2 33515314 Progesterone induces apoptosis by activation of caspase-8 and calcitriol via activation of caspase-9 pathways in ovarian and endometrial cancer cells in vitro. 2021 Apr 2
3 29301308 MSP-4, an Antimicrobial Peptide, Induces Apoptosis via Activation of Extrinsic Fas/FasL- and Intrinsic Mitochondria-Mediated Pathways in One Osteosarcoma Cell Line. 2018 Jan 2 1
4 30154785 RIPK1-RIPK3-MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils. 2018 1
5 30551620 23-Hydroxyursolic Acid Isolated from the Stem Bark of Cussonia bancoensis Induces Apoptosis through Fas/Caspase-8-Dependent Pathway in HL-60 Human Promyelocytic Leukemia Cells. 2018 Dec 13 1
6 30671458 Role of the Death Receptor and Endoplasmic Reticulum Stress Signaling Pathways in Polyphyllin I-Regulated Apoptosis of Human Hepatocellular Carcinoma HepG2 Cells. 2018 1
7 28182780 Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives. 2017 1
8 28184196 AG36 Inhibits Human Breast Cancer Cells Proliferation by Promotion of Apoptosis In vitro and In vivo. 2017 1
9 28460471 NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP. 2017 Apr 18 2
10 28610909 RIP1 has a role in CD40-mediated apoptosis in human follicular lymphoma cells. 2017 Nov 2
11 26984266 Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells. 2016 May 2
12 27064569 Anticancer Effects of 1,3-Dihydroxy-2-Methylanthraquinone and the Ethyl Acetate Fraction of Hedyotis Diffusa Willd against HepG2 Carcinoma Cells Mediated via Apoptosis. 2016 1
13 27176505 The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells. 2016 Jul 1
14 27551490 Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio. 2016 1
15 27565731 mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity. 2016 Sep 30 1
16 27695262 Kayeassamin A Isolated from the Flower of Mammea siamensis Triggers Apoptosis by Activating Caspase-3/-8 in HL-60 Human Leukemia Cells. 2016 Oct-Dec 1
17 27738323 Synergistic targeting of Sp1, a critical transcription factor for myeloma cell growth and survival, by panobinostat and proteasome inhibitors. 2016 Nov 29 2
18 27748905 Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces apoptosis via Fas-mediated pathway in HL-60 human leukemia cells. 2016 Dec 1
19 28675694 Benzyl isothiocyanate (BITC) induces apoptosis of GBM 8401 human brain glioblastoma multiforms cells via activation of caspase-8/Bid and the reactive oxygen species-dependent mitochondrial pathway. 2016 Dec 2
20 24840272 Nickel ions from a corroded cardiovascular stent induce monocytic cell apoptosis: Proposed impact on vascular remodeling and mechanism. 2015 Nov 1
21 25036678 Induction of apoptosis by 2,3-dehydrosilybin via a caspase-dependent pathway in human HeLa cells. 2014 2
22 25070834 SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells. 2014 Oct 1
23 25456851 Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines. 2014 Oct 1
24 25506265 Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells. 2014 1
25 23065354 The caspase pathway of linoelaidic acid (9t, 12t-c18:2)-induced apoptosis in human umbilical vein endothelial cells. 2013 Feb 2
26 23292890 Mechanisms of andrographolide-induced platelet apoptosis in human platelets: regulatory roles of the extrinsic apoptotic pathway. 2013 Nov 2
27 23618862 YM155 induces caspase-8 dependent apoptosis through downregulation of survivin and Mcl-1 in human leukemia cells. 2013 May 24 2
28 23652278 OSU-03012, a non-Cox inhibiting celecoxib derivative, induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway. 2013 Aug 1
29 23865778 Antiproliferative activity of abietane diterpenoids against human tumor cells. 2013 Aug 23 1
30 23940767 The Fas/Fas ligand death receptor pathway contributes to phenylalanine-induced apoptosis in cortical neurons. 2013 1
31 24168111 An investigation into the anticancer effects and mechanism of action of hop β-acid lupulone and its natural and synthetic derivatives in prostate cancer cells. 2013 2
32 21697648 Cadmium-induced apoptosis and necrosis in human osteoblasts: role of caspases and mitogen-activated protein kinases pathways. 2012 Feb 1
33 22297752 The effect of isolancifolide on the apoptosis in HL-60 cells through caspase-8-dependent and -independent pathways. 2012 Jan 1
34 22298457 Dehydrocorydaline inhibits breast cancer cells proliferation by inducing apoptosis in MCF-7 cells. 2012 1
35 22395735 Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis. 2012 Jun 1
36 22453599 Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells. 2012 Jul 1
37 22552576 Apoptosis induced by hepatitis B virus X protein in a CCL13-HBx stable cell line. 2012 Jul 3
38 22895075 CD44 ligation with A3D8 antibody induces apoptosis in acute myeloid leukemia cells through binding to CD44s and clustering lipid rafts. 2012 Nov 1
39 24031135 Mechanisms underlying production and externalization of oxidized phosphatidylserine in apoptosis: involvement of mitochondria. 2012 Mar 2
40 21107704 Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. 2011 Feb 1
41 21152878 Death receptor 5-mediated TNFR family signaling pathways modulate γ-humulene-induced apoptosis in human colorectal cancer HT29 cells. 2011 Feb 2
42 21229607 3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. 2011 Feb 1
43 21308745 Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. 2011 Apr 1
44 21437721 Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway. 2011 Jun 1
45 21691071 Caspase 3 is activated through caspase 8 instead of caspase 9 during H2O2-induced apoptosis in HeLa cells. 2011 1
46 21801359 5-allyl-7-gen-difluoromethoxychrysin enhances TRAIL-induced apoptosis in human lung carcinoma A549 cells. 2011 Jul 29 1
47 21881674 Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells. 2011 Nov 1
48 21903588 Characterization of Cholix toxin-induced apoptosis in HeLa cells. 2011 Oct 28 1
49 21951963 Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-κB activity. 2011 Nov 30 1
50 19784869 Danthron induced apoptosis through mitochondria- and caspase-3-dependent pathways in human brain glioblastoma multiforms GBM 8401 cells. 2010 Mar 1