Ceramides

caspase 8 ; Homo sapiens







22 Article(s)
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1 27487939 Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes. 2016 Aug 4 2
2 26232616 Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione. 2015 Nov 1
3 24044897 Cytosolic phospholipase A2α upregulation mediates apoptotic neuronal death induced by aggregated amyloid-β peptide1-42. 2013 Nov 1
4 23254292 Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer. 2012 Dec 20 1
5 19329756 Heat shock protein 90 inhibitor induces apoptosis and attenuates activation of hepatic stellate cells. 2009 Jul 1
6 18787411 Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. 2008 Oct 3
7 18948750 Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK. 2008 Nov 1 1
8 17191114 The role of membrane lipids in the induction of macrophage apoptosis by microparticles. 2007 Feb 1
9 17666435 GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis. 2007 Aug 15 2
10 16397504 Caspase-dependent and -independent cell death of Jurkat human leukemia cells induced by novel synthetic ceramide analogs. 2006 Mar 1
11 16624285 The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway. 2006 Jul 1 1
12 15849201 Caspase-dependent and -independent activation of acid sphingomyelinase signaling. 2005 Jul 15 1
13 15131591 Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways. 2004 Sep 1
14 15262979 Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis. 2004 Sep 24 4
15 12393559 Dexamethasone-induced apoptosis of thymocytes: role of glucocorticoid receptor-associated Src kinase and caspase-8 activation. 2003 Jan 15 3
16 12415011 Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase. 2002 Dec 1 2
17 12428923 Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cells. 2002 Sep 1
18 12437970 Ceramide induces neuronal apoptosis through the caspase-9/caspase-3 pathway. 2002 Nov 29 2
19 10722705 CD95(Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis. 2000 Mar 24 2
20 10747891 Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells. 2000 May 26 1
21 10792026 Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. 2000 May 9 1
22 9541007 Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide. 1998 Mar 20 2