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caspase 8 ; Homo sapiens







182 Article(s)
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151 10871865 p27KIP1 is down-regulated by two different mechanisms in human lymphoid cells undergoing apoptosis. 2000 Jun 22 2
152 10958671 Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria. 2000 Sep 1
153 10960761 Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner in human gastric adenocarcinoma cells. 2000 Oct 1 2
154 10964557 Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex. 2000 Sep 8 1
155 10964568 The three-dimensional solution structure and dynamic properties of the human FADD death domain. 2000 Sep 8 1
156 10972087 VEINCTR-N, an immunogenic epitope of Fas (CD95/Apo-I), and soluble Fas enhance T-cell apoptosis in vitro. II. Functional analysis and possible implications in HIV-1 disease. 2000 Jun 1
157 11004695 Frequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomas. 2000 Oct 2
158 11010806 Fas-mediated apoptosis of proliferating, transiently growth-arrested, and senescent normal human fibroblasts. 2000 Oct 10 1
159 11042678 Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells. 2000 Sep 1
160 11101870 Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. 2000 Dec 1
161 11110692 Interferon-gamma-induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8-dependent activation of caspase 3 family members. 2000 Dec 15 1
162 9880544 Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex. 1999 Jan 15 2
163 9891071 Cif (Cytochrome c efflux-inducing factor) activity is regulated by Bcl-2 and caspases and correlates with the activation of Bid. 1999 Feb 1
164 9971775 Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8. 1999 Mar 1
165 9973403 Elevation of mitochondrial transmembrane potential and reactive oxygen intermediate levels are early events and occur independently from activation of caspases in Fas signaling. 1999 Feb 1 1
166 10066378 The temporal relationship between protein phosphatase, mitochondrial cytochrome c release, and caspase activation in apoptosis. 1999 Mar 15 2
167 10088775 Tumor necrosis factor alpha regulation of the FAS-mediated apoptosis-signaling pathway in synovial cells. 1999 Mar 2
168 10328578 Apomodulation as a novel therapeutic concept for the regulation of apoptosis in rheumatoid synoviocytes. 1999 May 1
169 10444259 Increased activity of caspase 3 and caspase 8 in anti-Fas-induced apoptosis in lymphocytes from ageing humans. 1999 Aug 1
170 10477698 Modulation of caspase-8 and FLICE-inhibitory protein expression as a potential mechanism of Epstein-Barr virus tumorigenesis in Burkitt's lymphoma. 1999 Sep 1 1
171 10480431 CD95/Fas-triggered apoptosis of activated T lymphocytes is prevented by dendritic cells through a CD58-dependent mechanism. 1999 Sep 1
172 10508784 The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis. 1999 Sep 15 1
173 10508785 The atomic-resolution structure of human caspase-8, a key activator of apoptosis. 1999 Sep 15 1
174 10535957 A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2. 1999 Oct 26 1
175 9446604 An induced proximity model for caspase-8 activation. 1998 Jan 30 2
176 9606216 E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE. 1998 Jun 1 2
177 9654089 Molecular cloning and characterization of mouse caspase-8. 1998 Apr 15 5
178 9694885 Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B. 1998 Aug 14 1
179 9740801 Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. 1998 Sep 10 8
180 9840917 Inhibition of Fas-induced apoptosis by Bcl-2. 1998 Nov 19 5
181 9865748 Fas-mediated apoptosis in human prostatic carcinoma cell lines occurs via activation of caspase-8 and caspase-7. 1998 Dec 15 5
182 9190889 Affinity labeling displays the stepwise activation of ICE-related proteases by Fas, staurosporine, and CrmA-sensitive caspase-8. 1997 Jun 12 3