Cisplatin

caspase 8 ; Homo sapiens







91 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 21801448 Essential role of caspase-8 in p53/p73-dependent apoptosis induced by etoposide in head and neck carcinoma cells. 2011 Jul 31 1
52 20735432 Programmed cell death 4 enhances chemosensitivity of ovarian cancer cells by activating death receptor pathway in vitro and in vivo. 2010 Oct 2
53 21364680 Resistance to caspase-8 and -9 fragments in a malignant pleural mesothelioma cell line with acquired cisplatin-resistance. 2010 Sep 23 3
54 19276256 Enhancement of lexatumumab-induced apoptosis in human solid cancer cells by Cisplatin in caspase-dependent manner. 2009 Mar 15 2
55 19578756 Human bladder cancer cells undergo cisplatin-induced apoptosis that is associated with p53-dependent and p53-independent responses. 2009 Aug 2
56 19590723 TRAIL-induced cell death and caspase-8 activation are inhibited by cisplatin but not carboplatin. 2009 Jun 3
57 19625063 Oxidative stress sensitizes bladder cancer cells to TRAIL mediated apoptosis by down-regulating anti-apoptotic proteins. 2009 Sep 1
58 19852930 Association of caspase-8 mutation with chemoresistance to cisplatin in HOC313 head and neck squamous cell carcinoma cells. 2009 Dec 18 6
59 17021654 The apoptotic effect of intercalating agents on HPV-negative cervical cancer C-33A cells. 2007 Jul 2
60 17183590 Antiapoptotic mechanism of cannabinoid receptor 2 agonist on cisplatin-induced apoptosis in the HEI-OC1 auditory cell line. 2007 Mar 1
61 17452997 Bcl-2 cleavages at two adjacent sites by different caspases promote cisplatin-induced apoptosis. 2007 May 2
62 17574045 The essential role of the mitochondria and reactive oxygen species in Cisplatin-mediated enhancement of fas ligand-induced apoptosis in malignant pleural mesothelioma. 2007 Jul 1
63 17619073 Solamargine induces apoptosis and sensitizes breast cancer cells to cisplatin. 2007 Nov 1
64 17627812 Interferon-gamma mediated up-regulation of caspase-8 sensitizes medulloblastoma cells to radio- and chemotherapy. 2007 Aug 1
65 16009487 Upregulation of Bcl-2 is associated with cisplatin-resistance via inhibition of Bax translocation in human bladder cancer cells. 2006 Jun 8 1
66 16442262 Role of death receptor and mitochondrial pathways in conventional chemotherapy drug induction of apoptosis. 2006 Sep 1
67 17172403 Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. 2006 Dec 4
68 15863130 Sensitivity to Fas-mediated apoptosis in high-risk HPV-positive human cervical cancer cells: relationship with Fas, caspase-8, and Bid. 2005 May 1
69 15870947 Defects in apoptotic signal transduction in cisplatin-resistant non-small cell lung cancer cells. 2005 Jun 1
70 16044419 Biological and chemical inhibitors of NF-kappaB sensitize SiHa cells to cisplatin-induced apoptosis. 2005 Sep 1
71 16228292 BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53. 2005 Dec 1
72 15258564 Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro. 2004 Sep 16 3
73 15289875 Loss of caspase-8 activation pathway is a possible mechanism for CDDP resistance in human laryngeal squamous cell carcinoma, HEp-2 cells. 2004 Sep 6
74 15336528 Action of solamargine on TNFs and cisplatin-resistant human lung cancer cells. 2004 Sep 24 1
75 15386344 Long-term activation of SAPK/JNK, p38 kinase and fas-L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance. 2004 Dec 20 1
76 15566959 Dual apoptotic effect of Xrel3 c-Rel/NF-kappaB homolog in human cervical cancer cells. 2004 2
77 15604295 Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss. 2004 Dec 15 1
78 12543810 Failure of activation of caspase-9 induces a higher threshold for apoptosis and cisplatin resistance in testicular cancer. 2003 Jan 15 1
79 12690107 Adenoviral Bid overexpression induces caspase-dependent cleavage of truncated Bid and p53-independent apoptosis in human non-small cell lung cancers. 2003 Jul 11 1
80 12815464 Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line. 2003 Jul 2
81 12911332 Up-regulation of FLIP in cisplatin-selected HeLa cells causes cross-resistance to CD95/Fas death signalling. 2003 Nov 15 3
82 12912965 Role of antiapoptotic proteins in tumor necrosis factor-related apoptosis-inducing ligand and cisplatin-augmented apoptosis. 2003 Aug 1 1
83 12919886 Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential. 2003 Sep 3
84 14519653 Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells. 2003 Sep 15 2
85 11859411 Induction of apoptosis by chemotherapeutic drugs: the role of FADD in activation of caspase-8 and synergy with death receptor ligands in ovarian carcinoma cells. 2002 Mar 1
86 11872042 Cisplatin-induced in vivo differentiation of human embryonal carcinoma. 2002 Mar 1
87 12018840 Signaling and function of caspase and c-jun N-terminal kinase in cisplatin-induced apoptosis. 2002 Apr 30 2
88 11566177 Apaf-1 overexpression partially overcomes apoptotic resistance in a cisplatin-selected HeLa cell line. 2001 Sep 14 2
89 11703590 Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells. 2001 Nov 1
90 10663637 Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma. 2000 4
91 11156422 Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460. 2000 Dec 15 1