Vorinostat

caspase 8 ; Homo sapiens







21 Article(s)
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1 28099148 Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-α through up-regulation of TNF receptor 1 in lung cancer cells. 2017 Mar 14 1
2 27474150 FLIP: A Targetable Mediator of Resistance to Radiation in Non-Small Cell Lung Cancer. 2016 Oct 1
3 27863490 Suberoylanilide hydroxamic acid represses glioma stem-like cells. 2016 Nov 18 1
4 24651472 Antioxidants impair anti-tumoral effects of Vorinostat, but not anti-neoplastic effects of Vorinostat and caspase-8 downregulation. 2014 1
5 23590818 Combination of Vorinostat and caspase-8 inhibition exhibits high anti-tumoral activity on endometrial cancer cells. 2013 Aug 3
6 23868066 SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma. 2013 Jul 18 1
7 24236158 The anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) on the aggressive phenotypes of ovarian carcinoma cells. 2013 1
8 22154545 Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent. 2012 May 2
9 22322857 Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis. 2012 Aug 1
10 23086637 [Synergistic effect of histone deacetylase inhibitor suberoylanilide hydroxamic acid with imatinib on K562 cells]. 2012 Sep 1
11 19387079 Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications. 2009 Sep 1
12 19597472 Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8. 2009 Sep 3 2
13 19737941 Suberoylanilide hydroxamic acid sensitizes human oral cancer cells to TRAIL-induced apoptosis through increase DR5 expression. 2009 Sep 1
14 18636153 The role of oxidative stress in apoptosis induced by the histone deacetylase inhibitor suberoylanilide hydroxamic acid in human colon adenocarcinoma HT-29 cells. 2008 Aug 1
15 18765530 Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. 2008 Sep 1 1
16 18787411 Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. 2008 Oct 2
17 17351739 SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. 2007 Jul 1
18 18025281 Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells. 2007 Nov 1
19 18065490 Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells. 2007 Dec 2
20 16550602 The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, overcomes resistance of human breast cancer cells to Apo2L/TRAIL. 2006 Aug 15 1
21 15897598 Novel histone deacetylase inhibitors in the treatment of thyroid cancer. 2005 May 15 1