Reactive Oxygen Species

caspase 8 ; Homo sapiens







61 Article(s)
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1 34302634 Lactucin induces apoptosis through reactive oxygen species-mediated BCL-2 and CFLARL downregulation in Caki-1 cells. 2021 Oct 1
2 34479917 Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression. 2021 Sep-Oct 1
3 32093309 Bladder Cancer Chemosensitivity is Affected by Paraoxonase-2 Expression. 2020 Feb 20 1
4 32616191 The ethyl acetate extraction of Pileostegia tomentella (ZLTE) exerts anti-cancer effects on H1299 cells via ROS-induced canonical apoptosis. 2020 Jul 1
5 30309851 Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics. 2019 Mar 1
6 30365122 Vorinostat enhances gefitinib‑induced cell death through reactive oxygen species‑dependent cleavage of HSP90 and its clients in non‑small cell lung cancer with the EGFR mutation. 2019 Jan 2
7 31091501 Spermatogenesis disorder caused by T-2 toxin is associated with germ cell apoptosis mediated by oxidative stress. 2019 Aug 1
8 31392779 Cardiac glycoside sensitized hepatocellular carcinoma cells to TRAIL via ROS generation, p38MAPK, mitochondrial transition, and autophagy mediation. 2019 Nov 1
9 31542488 Decitabine promotes apoptosis in mesenchymal stromal cells isolated from patients with myelodysplastic syndromes by inducing reactive oxygen species generation. 2019 Nov 15 2
10 30009775 Proteasome mediated degradation of CDC25C and Cyclin B1 in Demethoxycurcumin treated human glioma U87 MG cells to trigger G2/M cell cycle arrest. 2018 Oct 1 1
11 30154785 RIPK1-RIPK3-MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils. 2018 2
12 30204479 Bixin Triggers Apoptosis of Human Hep3B Hepatocellular Carcinoma Cells: An Insight to Molecular and IN SILICO Approach. 2018 Aug-Sep 1
13 30211553 Reactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells. 2018 Sep 26 2
14 27993669 Contrasting effects of glutamine deprivation on apoptosis induced by conventionally used anticancer drugs. 2017 Mar 1
15 28154184 Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma. 2017 Apr 21 1
16 28238526 Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. 2017 Jun 1
17 28542135 Furanodienone induces G0/G1 arrest and causes apoptosis via the ROS/MAPKs-mediated caspase-dependent pathway in human colorectal cancer cells: a study in vitro and in vivo. 2017 May 25 1
18 28888620 The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production. 2017 Nov 6
19 29242562 ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line. 2017 Dec 14 5
20 26971531 Baicalein Induces Caspase-dependent Apoptosis Associated with the Generation of ROS and the Activation of AMPK in Human Lung Carcinoma A549 Cells. 2016 Mar 1
21 27221553 Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway. 2016 Jul 1
22 27393947 Syntheses and photodynamic activity of some glucose-conjugated BODIPY dyes. 2016 Oct 21 1
23 27571890 Baicalein induces apoptosis via ROS-dependent activation of caspases in human bladder cancer 5637 cells. 2016 Sep 3
24 25447764 The combination of adenosine deaminase inhibition and deoxyadenosine induces apoptosis in a human astrocytoma cell line. 2015 Jan 1
25 25586525 Luteolin acts as a radiosensitizer in non‑small cell lung cancer cells by enhancing apoptotic cell death through activation of a p38/ROS/caspase cascade. 2015 Mar 1
26 24716979 Curcumin inhibits MHCC97H liver cancer cells by activating ROS/TLR-4/caspase signaling pathway. 2014 2
27 24927175 Tazarotene induces apoptosis in human basal cell carcinoma via activation of caspase-8/t-Bid and the reactive oxygen species-dependent mitochondrial pathway. 2014 Oct 1
28 25018064 Potent proapoptotic actions of dihydroartemisinin in gemcitabine-resistant A549 cells. 2014 Oct 3
29 25112602 Cartilage polysaccharide induces apoptosis in K562 cells through a reactive oxygen species-mediated caspase pathway. 2014 Oct 1
30 25275027 Synergistic effects between catalase inhibitors and modulators of nitric oxide metabolism on tumor cell apoptosis. 2014 Oct 1
31 23536891 Ionizing radiation potentiates dihydroartemisinin-induced apoptosis of A549 cells via a caspase-8-dependent pathway. 2013 2
32 23685456 ROS and ERK1/2-mediated caspase-9 activation increases XAF1 expression in dexamethasone-induced apoptosis of EBV-transformed B cells. 2013 Jul 1
33 23826964 Brefeldin a induces apoptosis by activating the mitochondrial and death receptor pathways and inhibits focal adhesion kinase-mediated cell invasion. 2013 Nov 1
34 23892367 RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition. 2013 Oct 1
35 23921841 Licochalcone A enhances geldanamycin-induced apoptosis through reactive oxygen species-mediated caspase activation. 2013 1
36 22289270 Mancozeb-induced genotoxicity and apoptosis in cultured human lymphocytes. 2012 Jun 6 1
37 22365665 Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. 2012 Feb 24 1
38 22434375 Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells. 2012 Jun 1
39 20954801 Gallic acid-induced human pulmonary fibroblast cell death is accompanied by increases in ROS level and GSH depletion. 2011 Jan 1
40 21082355 Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism. 2011 Feb 2
41 21308745 Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. 2011 Apr 1
42 21519916 Cryptotanshinone enhances TNF-α-induced apoptosis in chronic myeloid leukemia KBM-5 cells. 2011 Jul 1
43 22160723 Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress. 2011 Dec 27 1
44 20799830 Single-cell analysis of dihydroartemisinin-induced apoptosis through reactive oxygen species-mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques. 2010 Jul-Aug 3
45 19166881 Human initiator caspases trigger apoptotic and autophagic phenotypes in Saccharomyces cerevisiae. 2009 Mar 2
46 19406930 Peroxiredoxin I contributes to TRAIL resistance through suppression of redox-sensitive caspase activation in human hepatoma cells. 2009 Jul 1
47 19481559 N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells. 2009 Aug 15 6
48 19646526 Protective role of cytosolic 2-cys peroxiredoxin in the TNF-alpha-induced apoptotic death of human cancer cells. 2009 Oct 15 1
49 18667818 Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. 2008 2
50 17031493 Caspase-8 dependent TRAIL-induced apoptosis in cancer cell lines is inhibited by vitamin C and catalase. 2007 Jan 1