25-hydroxycholesterol

3-hydroxy-3-methylglutaryl-CoA reductase ; Homo sapiens







13 Article(s)
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Title
Pub. Year
#Total Relationships
1 31902650 Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols. 2020 Feb 1 1
2 25759117 Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis. 2015 Jul 1
3 9059514 Studies on the relationships between 7 alpha-hydroxylation and the ability of 25- and 27-hydroxycholesterol to suppress the activity of HMG-CoA reductase. 1997 Feb 18 4
4 7717981 3'-untranslated sequences mediate post-transcriptional regulation of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA by 25-hydroxycholesterol. 1995 Apr 1 2
5 8579633 Toxicity of oxysterols to human monocyte-macrophages. 1995 Nov 1
6 8057282 Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription. 1994 Jul 22 1
7 8352528 Regulatory role of mevalonate in the growth of normal and neoplastic human mammary epithelial cells. 1993 Jul-Aug 2
8 1346397 Calcium ionophore treatment impairs the sterol-mediated suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3-hydroxy-3-methylglutaryl-coenzyme A synthase, and farnesyl diphosphate synthetase. 1992 Feb 5 1
9 1352965 Correlation among oxysterol potencies in the regulation of the degradation of 3-hydroxy-3-methylglutaryl CoA reductase, the repression of 3-hydroxy-3-methylglutaryl CoA synthase and affinities for the oxysterol receptor. 1992 Jul 15 1
10 1712015 Interrelationships between mevalonate metabolism and the mitogenic signaling pathway in T lymphocyte proliferation. 1991 Jul 5 2
11 2568358 Coordinate regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, and prenyltransferase synthesis but not degradation in HepG2 cells. 1989 Jul 25 1
12 2904178 Further characterization of a somatic cell mutant defective in regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1988 Nov 1
13 3390448 8-bromoadenosine cyclic 3',5'-phosphate rapidly increases 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA in human granulosa cells: role of cellular sterol balance in controlling the response to tropic stimulation. 1988 May 3 3