Pentostatin

adenosine deaminase ; Rattus norvegicus







40 Article(s)
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1 16542004 Conversion of viramidine to ribavirin in vivo by adenosine deaminase and its inhibition by 2'-deoxycoformycin. 2006 1
2 12771621 Therapeutic potential for transient inhibition of adenosine deaminase in systemic inflammatory response syndrome. 2003 May 2
3 10820140 First-pass disposition of (-)-6-aminocarbovir in rats: II. Inhibition of intestinal first-pass metabolism. 2000 Jun 1
4 9572907 Absorption and intestinal metabolism of purine dideoxynucleosides and an adenosine deaminase-activated prodrug of 2',3'-dideoxyinosine in the mesenteric vein cannulated rat ileum. 1998 May 1
5 9726984 Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinase. 1998 Sep 11 1
6 9013123 An adenosine deaminase inhibitor prevents puromycin aminonucleoside nephrotoxicity. 1997 3
7 9210198 Role of brain tissue localized purine metabolizing enzymes in the central nervous system delivery of anti-HIV agents 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats. 1997 Jun 1
8 9399998 Regulation of adenosine concentration and cytoprotective effects of novel reversible adenosine deaminase inhibitors. 1997 Dec 1
9 7640871 Immunosuppressive effect of 2'-deoxycoformycin (Pentostatin) for rat islet allotransplantation. 1995 May-Jun 3
10 8846098 Enhancement of NMDA-induced increases in levels of endogenous adenosine by adenosine deaminase and adenosine transport inhibition in rat striatum. 1995 Dec 8 1
11 7891860 Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions. 1994 Nov 1
12 8249784 Adenosine deaminase inhibition is not cardioprotective in the rat. 1993 Dec 2
13 8469375 Failure of 2'-deoxycoformycin to protect against transient forebrain ischemia in rat. 1993 Jan 4 4
14 1318679 Metabolism and pharmacokinetics of the anti-varicella-zoster virus agent 6-dimethylaminopurine arabinoside. 1992 Feb 1
15 1441846 Adenosine deaminase: physical and chemical properties of partially purified mitochondrial and cytosol enzyme from rat liver. 1992 2
16 1611498 Deoxycoformycin and oxypurinol: protection against focal ischemic brain injury in the rat. 1992 Feb 7 1
17 1729390 Rat brain adenosine deaminase after 2'-deoxycoformycin administration: biochemical properties and evidence for reduced enzyme levels detected by 2'-[3H]deoxycoformycin ligand binding. 1992 Feb 21
18 1671090 Brain adenosine and transmitter amino acid release from the ischemic rat cerebral cortex: effects of the adenosine deaminase inhibitor deoxycoformycin. 1991 Feb 2
19 1877368 Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism. 1991 May 1
20 1948767 Developmental toxicity of pentostatin (2'-deoxycoformycin) in rats and rabbits. 1991 Sep 3
21 2172653 H2O2-mediated cytotoxicity of rat pulmonary endothelial cells. Changes in adenosine triphosphate and purine products and effects of protective interventions. 1990 Nov 1
22 2179470 2'-Deoxycoformycin inhibition of adenosine deaminase in rat brain: in vivo and in vitro analysis of specificity, potency, and enzyme recovery. 1990 Apr 9
23 2572681 Adenosine receptor activation and the regulation of tyrosine hydroxylase activity in PC12 and PC18 cells. 1989 Dec 1
24 3262116 Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex. 1988 Oct 1
25 3263396 Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats. 1988 Nov 1
26 2825638 The mechanism by which adenosine decreases gluconeogenesis from lactate in isolated rat hepatocytes. 1987 Sep 1 1
27 3494649 An involvement of adenosine in cerebral blood flow regulation during hypercapnia. 1987 1
28 3499581 Pharmacokinetics of 2'-deoxycoformycin, an inhibitor of adenosine deaminase, in the rat. 1987 Sep 8
29 3485513 Chromosome anomalies associated with amplification of the adenosine deaminase gene (ADA) in rat hepatoma cells. 1986 3
30 3515350 Adenosine release from isolated rat adipocytes: influence of fat cell concentration and cell size. 1986 May 1
31 3877119 Effects of pentostatin (2'deoxycoformycin), an inhibitor of adenosine deaminase, on type II collagen-induced arthritis in rats. 1985 2
32 3877709 Interleukin 2 liberation and absorption capacities of rat T lymphocytes in conditions of severe adenylic nucleotide pool depletion due to adenosine deaminase deficiency. 1985 Oct 1
33 6358608 Morphologic changes and immunohistochemical localization of adenosine deaminase in tissues of rats given injections of 2'-deoxycoformycin. 1983 Nov 6
34 6600234 Increased adenosine deaminase synthesis and messenger RNA activity in deoxycoformycin-resistant cells. 1983 Jan 10 2
35 6604525 The control of adenosine concentration in polymorphonuclear leucocytes, cultured heart cells and isolated perfused heart from the rat. 1983 Aug 15 1
36 6605347 Amplification of adenosine deaminase gene sequences in deoxycoformycin-resistant rat hepatoma cells. 1983 Nov 10 5
37 6815190 Adenosine deaminase from deoxycoformycin-sensitive and -resistant rat hepatoma cells. Purification and characterization. 1982 Dec 10 5
38 6259294 Adenosine and cyclic AMP in rat cerebral cortical slices: effects of adenosine uptake inhibitors and adenosine deaminase inhibitors. 1981 Mar 2
39 6249264 Role of adenosine deaminase, ecto-(5'-nucleotidase) and ecto-(non-specific phosphatase) in cyanide-induced adenosine monophosphate catabolism in rat polymorphonuclear leucocytes. 1980 Mar 15 1
40 231980 The influence of adenosine on intermediary metabolism of isolated hepatocytes. 1979 1