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34358123 | Synthesis and Human Carbonic Anhydrase I, II, IX, and XII Inhibition Studies of Sulphonamides Incorporating Mono-, Bi- and Tricyclic Imide Moieties. | 2021 Jul 19 |
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| 2 |
31718943 | Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. | 2020 Jan 1 |
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| 3 |
31813300 | Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties. | 2020 Dec |
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| 4 |
31914827 | Synthesis and human carbonic anhydrase I, II, VA, and XII inhibition with novel amino acid-sulphonamide conjugates. | 2020 Dec |
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| 5 |
32058104 | Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes. | 2020 Mar |
2 |
| 6 |
32748253 | Evaluation of some thiophene-based sulfonamides as potent inhibitors of carbonic anhydrase I and II isoenzymes isolated from human erythrocytes by kinetic and molecular modelling studies. | 2020 Dec |
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| 7 |
32891000 | Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII. | 2020 Oct |
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| 8 |
32926233 | Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes. | 2020 Oct |
2 |
| 9 |
30312867 | 3-Aminobenzenesulfonamides incorporating acylthiourea moieties selectively inhibit the tumor-associated carbonic anhydrase isoform IX over the off-target isoforms I, II and IV. | 2019 Feb |
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| 10 |
30594030 | Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment. | 2019 Feb 15 |
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| 11 |
30811749 | Investigation of the effects of some sulfonamides on acetylcholinesterase and carbonic anhydrase enzymes. | 2019 May |
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| 12 |
30978604 | Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies. | 2019 Jun |
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| 13 |
31374520 | Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. | 2019 Oct |
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| 14 |
31419777 | Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells. | 2019 Nov 15 |
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| 15 |
31515058 | Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors. | 2019 Nov 1 |
2 |
| 16 |
29271264 | Inhibition studies of Brucella suis β-carbonic anhydrases with a series of 4-substituted pyridine-3-sulphonamides. | 2018 Dec |
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| 17 |
29324250 | Novel sulfonamide incorporating piperazine, aminoalcohol and 1,3,5-triazine structural motifs with carbonic anhydrase I, II and IX inhibitory action. | 2018 Apr |
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| 18 |
28024887 | 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations. | 2017 Feb 1 |
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| 19 |
28161252 | Synthesis and biological evaluation of cyclic imides incorporating benzenesulfonamide moieties as carbonic anhydrase I, II, IV and IX inhibitors. | 2017 Mar 1 |
2 |
| 20 |
28256371 | Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects. | 2017 Apr 1 |
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| 21 |
28318894 | Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties. | 2017 Apr 15 |
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| 22 |
28802125 | Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies. | 2017 Oct 20 |
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| 23 |
26741028 | 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. | 2016 Jan 28 |
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| 24 |
26744900 | Synthesis and evaluation of sulfonamide-bearing thiazole as carbonic anhydrase isoforms hCA I and hCA II. | 2016 Dec |
2 |
| 25 |
27234893 | Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines. | 2016 Jul 1 |
2 |
| 26 |
27353698 | A class of sulfonamides as carbonic anhydrase I and II inhibitors. | 2016 |
1 |
| 27 |
27396930 | Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties. | 2016 Sep 15 |
1 |
| 28 |
27435177 | Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides. | 2016 |
1 |
| 29 |
24666294 | Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. | 2015 Feb |
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| 30 |
24758348 | Intrinsic thermodynamics of sulfonamide inhibitor binding to human carbonic anhydrases I and II. | 2015 Apr |
1 |
| 31 |
25089707 | New series of sulfonamides containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase XII. | 2015 Jun |
1 |
| 32 |
25912674 | Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives. | 2015 |
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| 33 |
26160114 | Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms. | 2015 Aug 28 |
1 |
| 34 |
26233435 | Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity. | 2015 Sep 15 |
1 |
| 35 |
26276436 | Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. | 2015 Sep 18 |
1 |
| 36 |
26639945 | Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity. | 2015 Dec 15 |
1 |
| 37 |
24589511 | Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties. | 2014 Apr 1 |
1 |
| 38 |
25267005 | Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones. | 2014 Nov 1 |
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| 39 |
22146078 | Docking, CoMFA and CoMSIA studies of a series of sulfonamides derivatives as carbonic anhydrase I inhibitors. | 2013 Apr |
1 |
| 40 |
23352754 | o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII. | 2013 Mar 15 |
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| 41 |
23859774 | 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies. | 2013 Sep 1 |
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| 42 |
22181786 | Quantum chemical QSAR models to distinguish between inhibitory activities of sulfonamides against human carbonic anhydrases I and II and bovine IV isozymes. | 2012 Apr |
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| 43 |
22733110 | Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases. | 2012 Aug 25 |
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| 44 |
23067387 | Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibit α- and β-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms. | 2012 Nov 26 |
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| 45 |
21549597 | Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. | 2011 Jun 1 |
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| 46 |
20166929 | Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII. | 2010 |
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| 47 |
20299219 | Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides. | 2010 Apr 15 |
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20624682 | Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors. | 2010 Aug 1 |
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19193158 | Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. | 2009 Feb 12 |
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19201197 | Carbonic anhydrase inhibitors. The nematode alpha-carbonic anhydrase of Caenorhabditis elegans CAH-4b is highly inhibited by 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides. | 2009 Apr 15 |
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