Bosentan

endothelin 1 ; Rattus norvegicus







87 Article(s)
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51 10535692 Nonpeptide endothelin receptor antagonists attenuate the pressor effect of diaspirin-crosslinked hemoglobin in rat. 1999 Mar 2
52 10637124 Evolution of streptozotocin-pancreatic damage in the rat: modulatory effect of endothelins on the nitridergic and prostanoid pathway. 1999 Dec 2
53 9535432 Endothelin-1 regulates tone of isolated small arteries in the rat: effect of hyperendothelinemia. 1998 Apr 2
54 9537672 Role of endogenous endothelin-1 in stress-induced gastric mucosal damage and acid secretion in rats. 1998 Jan 2 1
55 9595437 Nuclear Ca2+ signaling to endothelin-1 in rat aortic smooth-muscle cells. 1998 1
56 9605569 Endothelin receptors mediating contraction of rat and human pulmonary resistance arteries: effect of chronic hypoxia in the rat. 1998 Apr 1
57 9672179 The effect of endothelin and its antagonist Bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver. 1998 Jun 1
58 9085162 Bosentan, a novel synthetic mixed-type endothelin receptor antagonist, attenuates acute gastric mucosal lesions induced by indomethacin and HCl in the rat: role of endogenous endothelin-1. 1997 Apr 1
59 9176305 Endothelin-1 in rat endotoxemia: mRNA expression and vasoreactivity in pulmonary and systemic circulations. 1997 May 2
60 9246031 Gastric mucosal injury induced by local ischemia-reperfusion in rats. Role of endogenous endothelin-1 and free radical. 1997 Jul 1
61 9324107 Reactivity of mesenteric arteries from fructose hypertensive rats to endothelin-1. 1997 Sep 3
62 9338430 Nonspecific endothelin-receptor antagonist blunts monocrotaline-induced pulmonary hypertension in rats. 1997 Oct 2
63 9401760 Subtypes of endothelin receptors that mediate venous effects of endothelin-1 in anaesthetized rats. 1997 Nov 1
64 9403621 Chronic endothelin receptor blockade attenuates progressive ventricular dilation and improves cardiac function in rats with myocardial infarction: possible involvement of myocardial endothelin system in ventricular remodeling. 1997 Dec 2 2
65 9444527 Evaluation of bosentan, pinacidil and nitroprusside on human pulmonary arteries: comparison with rat pulmonary arteries. 1997 3
66 8602109 Selective and non-selective ET antagonists reveal an ETB receptors mediated ET-1-induced behavioural effect in conscious rats. 1996 1
67 8681627 Endothelin-1 does not mediate the endothelium-dependent hypoxic contractions of small pulmonary arteries in rats. 1996 Jul 1
68 8899066 The effect of endothelin receptor blockade on the development of the Sephadex-induced inflammation in the rat lung. 1996 Oct 4
69 8916269 Action and binding of the endothelin antagonist bosentan on astrocytes of cultured rat central nervous system. Electrophysiological and autoradiographic studies. 1996 Oct 22 1
70 8997390 Differential regulation of renal regional blood flow by endothelin-1. 1996 Dec 1
71 7485537 Expression of endothelins 1 and 3 in the rat kidney. 1995 Oct 2
72 7498305 Beneficial effects of the endothelin receptor antagonist bosentan on myocardial and endothelial injury following ischaemia/reperfusion in the rat. 1995 Sep 5 1
73 7544236 Endothelin-1 expression in blood vessels of DOCA-salt hypertensive rats treated with the combined ETA/ETB endothelin receptor antagonist bosentan. 1995 Mar 5
74 7582486 Actions of endothelins and sarafotoxin 6c in the rat isolated perfused lung. 1995 Jun 1
75 7721389 Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist. 1995 Apr 1
76 7721390 ETA and ETB receptors mediate contraction to endothelin-1 in renal artery of aging SHR. Effects of FR139317 and bosentan. 1995 Apr 1
77 7843769 Different mechanisms of endothelial dysfunction with aging and hypertension in rat aorta. 1995 Feb 1
78 7869843 Bosentan antagonizes the effects of endothelin-1 on rat gastric blood flow and mucosal integrity. 1995 3
79 8528554 Effects of the ETA/ETB receptor antagonist, bosentan on endothelin-1-induced myocardial ischaemia and oedema in the rat. 1995 Sep 4
80 8546870 Ca(2+)-activated Cl- and K+ channels and their modulation by endothelin-1 in rat pulmonary arterial smooth muscle cells. 1995 Sep 1
81 8564194 Antihypertensive effect of an endothelin receptor antagonist in DOCA-salt spontaneously hypertensive rats. 1995 Aug 1
82 8587339 Endothelin receptors that modulate contraction of the rat fundus. 1995 1
83 7858876 Characterization of receptors mediating vascular responses to endothelin-1 in the conscious rat. 1994 Nov 2
84 7858879 Role of endogenous endothelin in myocardial and coronary endothelial injury after ischaemia and reperfusion in rats: studies with bosentan, a mixed ETA-ETB antagonist. 1994 Nov 1
85 7921608 Effects of bosentan (Ro 47-0203), an ETA-, ETB-receptor antagonist, on regional haemodynamic responses to endothelins in conscious rats. 1994 Jul 2
86 7957619 Effect of BQ-123 and Ro 47-0203 (bosentan) on endothelin-induced vasoconstriction in the rat skin. 1994 Jul 21 2
87 8035319 Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. 1994 Jul 1