pyrazolanthrone

matrix metallopeptidase 2 ; Homo sapiens







22 Article(s)
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1 31894675 [Effects of dihydromyricetin on the migration and invasion of human gastric cancer MKN45 cells and its mechanism]. 2019 Sep 2
2 29766185 The curcumin derivative WZ35 activates ROS-dependent JNK to suppress hepatocellular carcinoma metastasis. 2018 May 23 1
3 24510324 Antitumor effects of the flavone chalcone: inhibition of invasion and migration through the FAK/JNK signaling pathway in human gastric adenocarcinoma AGS cells. 2014 Jun 1
4 24841706 Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways. 2014 Jul 1
5 25204501 Astrocyte elevated gene-1 (AEG-1) promotes osteosarcoma cell invasion through the JNK/c-Jun/MMP-2 pathway. 2014 Oct 3 1
6 25316568 Simvastatin induces NFκB/p65 down-regulation and JNK1/c-Jun/ATF-2 activation, leading to matrix metalloproteinase-9 (MMP-9) but not MMP-2 down-regulation in human leukemia cells. 2014 Dec 15 1
7 23786715 Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. 2013 Jun 20 1
8 23950935 Mechanical stretch increases MMP-2 production in vascular smooth muscle cells via activation of PDGFR-β/Akt signaling pathway. 2013 1
9 21468925 Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways. 2011 Jan 1
10 19633975 Antimetastatic potential of fisetin involves inactivation of the PI3K/Akt and JNK signaling pathways with downregulation of MMP-2/9 expressions in prostate cancer PC-3 cells. 2010 Jan 1
11 19887895 Induction of tissue inhibitor of matrix metalloproteinase-2 by cholesterol depletion leads to the conversion of proMMP-2 into active MMP-2 in human dermal fibroblasts. 2010 Jan 31 1
12 20136087 Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. 2010 Mar 10 1
13 20492175 Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-kappaB and AP-1. 2010 Jan-Feb 1
14 20607722 Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion. 2010 Sep 1
15 20688742 Downregulation of matrix metalloproteinase-2 in corneal fibroblasts by interleukin-1 receptor antagonist released from corneal epithelial cells. 2010 Dec 1
16 19178296 Alpha-mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway. 2009 Feb 25 1
17 19338750 Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells. 2009 Mar 20 1
18 18455449 JNK as a positive regulator of angiogenic potential in endothelial cells. 2008 Jul 2
19 16672691 JNK and PI3K differentially regulate MMP-2 and MT1-MMP mRNA and protein in response to actin cytoskeleton reorganization in endothelial cells. 2006 Oct 1
20 16000878 Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells. 2005 Jun 30 1
21 15386367 Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts. 2004 Dec 10 2
22 12909329 Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-alpha in cultured human umbilical vein endothelial cells. 2003 Aug 1 1