| 1 |
34742012 | Inhibition of SREBP-mediated lipid biosynthesis and activation of multiple anticancer mechanisms by platinum complexes: Ascribe possibilities of new antitumor strategies. | 2022 Jan 5 |
1 |
| 2 |
32065674 | A Phytosterolemic Mixture of Sterols Inhibits Cholesterol Synthesis, Esterification, and Low-Density Lipoprotein Receptor mRNA Abundance in HepG2 Cells. | 2020 Mar |
2 |
| 3 |
32727844 | Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. | 2020 Sep 25 |
2 |
| 4 |
31795497 | Genes Potentially Associated with Familial Hypercholesterolemia. | 2019 Nov 29 |
1 |
| 5 |
26153245 | Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease. | 2015 Oct |
1 |
| 6 |
24158702 | Molecular pathways: sterols and receptor signaling in cancer. | 2014 Jan 1 |
1 |
| 7 |
24770487 | Protein phosphatase 2A (PP2A) regulates low density lipoprotein uptake through regulating sterol response element-binding protein-2 (SREBP-2) DNA binding. | 2014 Jun 13 |
2 |
| 8 |
24899155 | Serum lipid responses to weight loss differ between overweight adults with familial hypercholesterolemia and those with familial combined hyperlipidemia. | 2014 Aug |
1 |
| 9 |
22153697 | Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins. | 2012 Feb |
1 |
| 10 |
22936343 | Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis. | 2012 Nov |
2 |
| 11 |
21294679 | Organelle stress-induced activating transcription factor-3 downregulates low-density lipoprotein receptor expression in Sk-Hep1 human liver cells. | 2011 Apr |
1 |
| 12 |
21559365 | Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake. | 2011 Apr 29 |
2 |
| 13 |
20863500 | Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes. | 2010 Nov |
1 |
| 14 |
19322023 | Sterol-independent repression of low density lipoprotein receptor promoter by peroxisome proliferator activated receptor gamma coactivator-1alpha (PGC-1alpha). | 2009 Jun 30 |
1 |
| 15 |
16292665 | Human low-density lipoprotein receptor gene and its regulation. | 2006 Jan |
1 |
| 16 |
16415294 | A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity. | 2006 May |
1 |
| 17 |
16787396 | Dynamin is involved in endolysosomal cholesterol delivery to the endoplasmic reticulum: role in cholesterol homeostasis. | 2006 Jul |
1 |
| 18 |
23105564 | Estradiol regulates insulin dependent stimulation of LDL-receptor expression in HepG(2) cells. | 2006 Mar |
1 |
| 19 |
16054075 | Dual regulation of the LDL receptor--some clarity and new questions. | 2005 May |
1 |
| 20 |
15514256 | Soy isoflavones affect sterol regulatory element binding proteins (SREBPs) and SREBP-regulated genes in HepG2 cells. | 2004 Nov |
1 |
| 21 |
12718903 | Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells. | 2003 May |
1 |
| 22 |
11792717 | A mutation (-49C>T) in the promoter of the low density lipoprotein receptor gene associated with familial hypercholesterolemia. | 2002 Jan |
1 |
| 23 |
11997513 | Critical role of diacylglycerol- and phospholipid-regulated protein kinase C epsilon in induction of low-density lipoprotein receptor transcription in response to depletion of cholesterol. | 2002 Jun |
2 |
| 24 |
12110376 | Elevated uptake of low density lipoprotein by drug resistant human leukemic cell lines. | 2002 Jun 15 |
1 |
| 25 |
12235180 | Identification of Egr1 as the oncostatin M-induced transcription activator that binds to sterol-independent regulatory element of human LDL receptor promoter. | 2002 Sep |
2 |
| 26 |
11250935 | Requirement of Sp1 and estrogen receptor alpha interaction in 17beta-estradiol-mediated transcriptional activation of the low density lipoprotein receptor gene expression. | 2001 Apr |
4 |
| 27 |
11416012 | Concerted transcriptional activation of the low density lipoprotein receptor gene by insulin and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase a, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase signaling pathways. | 2001 Jul |
3 |
| 28 |
11483628 | CTP:phosphocholine cytidylyltransferase, a new sterol- and SREBP-responsive gene. | 2001 Aug |
1 |
| 29 |
11545736 | Transcription factor MIZ-1 is regulated via microtubule association. | 2001 Aug |
2 |
| 30 |
11726974 | SCAP ligands are potent new lipid-lowering drugs. | 2001 Dec |
4 |
| 31 |
11795856 | Growth modulation of low density lipoprotein receptor sterol sensitivity in cultured human fibroblasts. | 2001 Nov |
2 |
| 32 |
10671569 | Identification of a novel sterol-independent regulatory element in the human low density lipoprotein receptor promoter. | 2000 Feb 18 |
2 |
| 33 |
10841543 | Nutrient regulation of gene expression by the sterol regulatory element binding proteins: increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivo. | 2000 Jun 6 |
1 |
| 34 |
10894816 | Interleukin-6 stimulates LDL receptor gene expression via activation of sterol-responsive and Sp1 binding elements. | 2000 Jul |
2 |
| 35 |
9989262 | The physiological role of sterol regulatory element-binding protein-2 in cultured human cells. | 1999 Jan 4 |
1 |
| 36 |
10037774 | Induction of low density lipoprotein receptor (LDLR) transcription by oncostatin M is mediated by the extracellular signal-regulated kinase signaling pathway and the repeat 3 element of the LDLR promoter. | 1999 Mar 5 |
2 |
| 37 |
10391894 | One-way cross-talk between p38(MAPK) and p42/44(MAPK). Inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade. | 1999 Jul 9 |
1 |
| 38 |
9478045 | Dietary fatty acids and the regulation of plasma low density lipoprotein cholesterol concentrations. | 1998 Feb |
2 |
| 39 |
9624172 | Differential roles of extracellular signal-regulated kinase-1/2 and p38(MAPK) in interleukin-1beta- and tumor necrosis factor-alpha-induced low density lipoprotein receptor expression in HepG2 cells. | 1998 Jun 19 |
2 |
| 40 |
9641167 | Cytokine regulation of low-density lipoprotein receptor gene transcription in human mesangial cells. | 1998 Jun |
1 |
| 41 |
9651391 | CBP is required for sterol-regulated and sterol regulatory element-binding protein-regulated transcription. | 1998 Jul 10 |
1 |
| 42 |
9717725 | Sterol-independent, sterol response element-dependent, regulation of low density lipoprotein receptor gene expression. | 1998 Aug |
3 |
| 43 |
9164239 | Evolution of processes and regulators of lipoprotein synthesis: from birds to mammals. | 1997 May |
1 |
| 44 |
9275065 | Androgen receptor-mediated antagonism of estrogen-dependent low density lipoprotein receptor transcription in cultured hepatocytes. | 1997 Sep |
2 |
| 45 |
9321669 | Identification of essential nucleotides of the FP1 element responsible for enhancement of low density lipoprotein receptor gene transcription. | 1997 Oct 15 |
1 |
| 46 |
9409246 | Upregulation of low density lipoprotein receptor by gemfibrozil, a hypolipidemic agent, in human hepatoma cells through stabilization of mRNA transcripts. | 1997 Nov |
1 |
| 47 |
9458267 | Decreased feedback regulation of low density lipoprotein receptor activity by sterols in leukemic cells from patients with acute myelogenous leukemia. | 1997 Dec |
3 |
| 48 |
8636148 | SREBP-1 mediates activation of the low density lipoprotein receptor promoter by insulin and insulin-like growth factor-I. | 1996 Mar 22 |
1 |
| 49 |
8820113 | Effects of cyclosporin on cholesterol 27-hydroxylation and LDL receptor activity in HepG2 cells. | 1996 Jan |
1 |
| 50 |
8932516 | Serum response element-like sequences of the human low density lipoprotein receptor promoter: possible regulation sites for sterol-independent transcriptional activation. | 1996 Feb |
2 |