Lovastatin

low density lipoprotein receptor ; Homo sapiens







40 Article(s)
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1 28802576 Atorvastatin and lovastatin, but not pravastatin, increased cellular complex formation between PCSK9 and the LDL receptor in human hepatocyte-like C3A cells. 2017 Oct 7 1
2 25395200 Clinically used selective oestrogen receptor modulators increase LDL receptor activity in primary human lymphocytes. 2015 Mar 2
3 22653811 JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. 2012 Dec 3
4 21994451 Cholesterol depletion of hepatoma cells impairs hepatitis B virus envelopment by altering the topology of the large envelope protein. 2011 Dec 1
5 20459026 [Establishment of a model for evaluating hypolipidemic effect in HepG2 cells]. 2010 Mar 1
6 21118482 Synergic effect of eicosapentaenoic acid and lovastatin on gene expression of HMGCoA reductase and LDL receptor in cultured HepG2 cells. 2010 Nov 30 3
7 18266936 Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts. 2008 May 2
8 15025528 Gene transfer into human hepatoma cells by receptor-associated protein/polylysine conjugates. 2004 Mar-Apr 2
9 15485695 Synergistic upregulation of low-density lipoprotein receptor activity by tamoxifen and lovastatin. 2004 Nov 1 2
10 12208479 The effects of lovastatin and simvastatin on the diurnal periodicity of plasma mevalonate concentrations in patients with heterozygous familial hypercholesterolemia. 2002 Nov 1
11 11728391 Effect of atorvastatin, simvastatin, and lovastatin on the metabolism of cholesterol and triacylglycerides in HepG2 cells. 2001 Dec 1 2
12 9555954 Three-fold effect of lovastatin treatment on low density lipoprotein metabolism in subjects with hyperlipidemia: increase in receptor activity, decrease in apoB production, and decrease in particle affinity for the receptor. Results from a novel triple-tracer approach. 1998 Apr 2
13 9678770 The effects of diet and lovastatin on regression of fatty streak lesions and on hepatic and intestinal mRNA levels for the LDL receptor and HMG CoA reductase in F1B hamsters. 1998 May 2
14 9199267 Surface expression of low density lipoprotein receptor in EBV-transformed lymphocytes: characterization and use for studying familial hypercholesterolemia. 1997 Jun 1
15 8628597 Treatment of familial hypercholesterolemia in children and adolescents: effect of lovastatin. Canadian Lovastatin in Children Study Group. 1996 May 1
16 8663292 Lipoprotein lipase binds to low density lipoprotein receptors and induces receptor-mediated catabolism of very low density lipoproteins in vitro. 1996 Jul 19 1
17 8765518 New low-density lipoprotein receptor upregulators acting via a novel mechanism. 1996 Aug 16 2
18 8800498 Abnormal regulation of the LDL-R and HMG CoA reductase genes in subjects with familial hypercholesterolemia with the "French Canadian mutation". 1996 Jul 4
19 8719939 Is responsiveness to lovastatin in familial hypercholesterolaemia heterozygotes influenced by the specific mutation in the low-density lipoprotein receptor gene? 1995 Dec 1
20 7728297 In-vitro effect of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors on non-hepatic LDL receptor activity: evidence of lack of stimulatory effect of pravastatin. 1994 Dec 1
21 8295321 Hypercholesterolemia in postmenopausal women. Metabolic defects and response to low-dose lovastatin. 1994 Feb 9 1
22 8263421 Lovastatin enhances hepatic uptake of low density lipoprotein in humans. 1993 Nov 1
23 8345800 The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism. 1993 Jul 1
24 8385478 Effects of lovastatin on the levels, structure, and atherogenicity of VLDL in patients with moderate hypertriglyceridemia. 1993 Apr 1
25 1431581 Cholesteryl ester storage disease: complex molecular effects of chronic lovastatin therapy. 1992 Jul 2
26 1919427 Influence of lovastatin therapy on metabolism of low density lipoproteins in mixed hyperlipidaemia. 1991 Oct 1
27 1986017 Coinheritance of two mild defects in low density lipoprotein receptor function produces severe hypercholesterolemia. 1991 Jan 1
28 2086705 Mitogenic stimulation alters the regulation of LDL receptor gene expression in human lymphocytes. 1990 Nov 1
29 2176080 The effect of (-)-hydroxycitrate on the activity of the low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase levels in the human hepatoma cell line Hep G2. 1990 Nov 15 1
30 2299987 The influence of apolipoprotein E phenotype on the response to lovastatin therapy in patients with heterozygous familial hypercholesterolemia. 1990 Feb 1
31 2310768 Cellular cholesterol metabolism in mitogen-stimulated lymphocytes--requirement for de novo synthesis. 1990 Feb 19 1
32 2360916 Effects of lovastatin therapy on LDL receptor activity in circulating monocytes and on structure and composition of plasma lipoproteins. 1990 May 3
33 2394831 Lack of effect of lovastatin therapy on the parameters of whole-body cholesterol metabolism. 1990 Sep 1
34 2552800 Normalization of LDL receptor function by lymphocytes of patients with heterozygous familial hypercholesterolemia after treatment with plasma cholesterol lowering agents. 1989 Sep 1
35 2725293 Reduction in plasma low-density lipoprotein cholesterol and urinary mevalonic acid by lovastatin in patients with heterozygous familial hypercholesterolemia. 1989 Jun 2
36 2741883 Reappraisal of partial ileal bypass for the treatment of familial hypercholesterolemia. 1989 Jul 1
37 2912432 Identification of low density lipoprotein receptor abnormalities by assaying functional receptors on proliferating lymphocytes. 1989 Jan-Feb 1
38 3029155 The effect of mevinolin on steroidogenesis in patients with defects in the low density lipoprotein receptor pathway. 1987 Mar 1
39 6087838 Inhibition of cholesterol synthesis by mevinolin stimulates low density lipoprotein receptor activity in human monocyte-derived macrophages. 1984 Jul 4
40 6569064 Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia. 1984 Dec 5