| 1 |
29996281 | [The influence of CYP2A6 polymorphism on adjuvant S-1 chemotherapy outcomes in patients with curatively resected gastric cancer]. | 2018 Jun 26 |
1 |
| 2 |
26715117 | Associations between CYP2A6 polymorphisms and outcomes of adjuvant S-1 chemotherapy in patients with curatively resected gastric cancer. | 2017 Jan |
2 |
| 3 |
28347333 | A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis. | 2017 Mar 27 |
2 |
| 4 |
25002745 | Effect of CYP2A6 genetic polymorphism on the metabolic conversion of tegafur to 5-fluorouracil and its enantioselectivity. | 2014 Sep |
1 |
| 5 |
23982118 | Phase I clinical and pharmacokinetic/pharmacogenetic study of a triplet regimen of S-1/irinotecan/oxaliplatin in patients with metastatic colorectal or gastric cancer. | 2013 Nov |
1 |
| 6 |
22322240 | Characteristic CYP2A6 genetic polymorphisms detected by TA cloning-based sequencing in Chinese digestive system cancer patients with S-1 based chemotherapy. | 2012 May |
2 |
| 7 |
21521021 | Association analysis of CYP2A6 genotypes and haplotypes with 5-fluorouracil formation from tegafur in human liver microsomes. | 2011 Apr |
2 |
| 8 |
20463005 | Formation pathways of gamma-butyrolactone from the furan ring of tegafur during its conversion to 5-fluorouracil. | 2010 Aug |
2 |
| 9 |
19604090 | Association of CYP2A6 polymorphisms with S-1 plus docetaxel therapy outcomes in metastatic gastric cancer. | 2009 Jul |
1 |
| 10 |
18212800 | The CYP2A6*4 allele is determinant of S-1 pharmacokinetics in Japanese patients with non-small-cell lung cancer. | 2008 Apr |
1 |
| 11 |
16897985 | Rapid development of S-1 in the west for therapy of advanced gastric carcinoma. | 2006 Jun |
1 |
| 12 |
16145066 | Phase I pharmacokinetic study of S-1 plus cisplatin in patients with advanced gastric carcinoma. | 2005 Oct 1 |
1 |
| 13 |
15618749 | The contribution of cytochrome P450 to the metabolism of tegafur in human liver. | 2003 |
1 |
| 14 |
12042667 | A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur. | 2002 Jun |
2 |
| 15 |
12172220 | Characterization of a genotype previously designated as CYP2A6 D-type: CYP2A6*4B, another entire gene deletion allele of the CYP2A6 gene in Japanese. | 2002 Aug |
1 |
| 16 |
11376561 | Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur. | 2001 May |
2 |
| 17 |
11106261 | Bioactivation of tegafur to 5-fluorouracil is catalyzed by cytochrome P-450 2A6 in human liver microsomes in vitro. | 2000 Nov |
1 |