| 1 |
34476898 | Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes. | 2022 Jan |
1 |
| 2 |
34478556 | Nicotine Metabolism Predicted by CYP2A6 Genotypes in Relation to Smoking Cessation: A Systematic Review. | 2022 Mar 26 |
4 |
| 3 |
35197312 | CYP2C19 plays a major role in the hepatic N-oxidation of cotinine. | 2022 Feb 23 |
1 |
| 4 |
35427216 | Mining of molecular insights of CYP2A6 and its variants complex with coumarin (CYP2A6*-coumarin) using molecular dynamics simulation. | 2022 Apr 15 |
1 |
| 5 |
34165800 | The Role of Pharmacogenetics in Smoking. | 2021 Sep |
2 |
| 6 |
34520119 | Nicotine metabolism and its association with CYP2A6 genotype among Indigenous people in Alaska who smoke. | 2021 Nov |
3 |
| 7 |
34576282 | Deciphering Structural Alterations Associated with Activity Reductions of Genetic Polymorphisms in Cytochrome P450 2A6 Using Molecular Dynamics Simulations. | 2021 Sep 19 |
1 |
| 8 |
30815984 | Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity. | 2020 Jan |
2 |
| 9 |
31578905 | Structure-activity relationship and in vitro inhibition of human cytochrome CYP2A6 and CYP2A13 by flavonoids. | 2020 Jun |
1 |
| 10 |
31628204 | The Novel CYP2A6 Inhibitor, DLCI-1, Decreases Nicotine Self-Administration in Mice. | 2020 Jan |
4 |
| 11 |
32131765 | Association of CYP2A6 gene deletion with cancers in Japanese elderly: an autopsy study. | 2020 Mar 4 |
1 |
| 12 |
32350062 | Nitric Oxide Mediated Degradation of CYP2A6 via the Ubiquitin-Proteasome Pathway in Human Hepatoma Cells. | 2020 Jul |
2 |
| 13 |
32496054 | Impact of E-Cigarette Liquid Flavoring Agents on Activity of Microsomal Recombinant CYP2A6, the Primary Nicotine-Metabolizing Enzyme. | 2020 Jul 20 |
5 |
| 14 |
33329709 | Effects of Genetic Polymorphisms of Drug Transporter ABCB1 (MDR1) and Cytochrome P450 Enzymes CYP2A6, CYP2B6 on Nicotine Addiction and Smoking Cessation. | 2020 |
1 |
| 15 |
33375250 | Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation. | 2020 Dec 26 |
3 |
| 16 |
30381441 | Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes. | 2019 Feb |
4 |
| 17 |
30611298 | Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci. | 2019 Jan 5 |
2 |
| 18 |
31453782 | Associations of CYP2A6 Gene Polymorphism with Smoking Status Among Jordanians: Gender-Related Differences. | 2019 |
3 |
| 19 |
31584787 | Genetically determined metabolism of nicotine and its clinical significance. | 2019 Oct 4 |
4 |
| 20 |
28032407 | CYP2A6 metabolism in the development of smoking behaviors in young adults. | 2018 Jan |
2 |
| 21 |
28290528 | Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain. | 2018 Jan |
3 |
| 22 |
28472521 | The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings. | 2018 Mar 6 |
1 |
| 23 |
29158210 | Longitudinal Influence of Pregnancy on Nicotine Metabolic Pathways. | 2018 Feb |
5 |
| 24 |
29232328 | Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. | 2018 Jan |
7 |
| 25 |
29788791 | Nicotine metabolite ratio and smoking outcomes using nicotine replacement therapy and varenicline among smokers with and without psychiatric illness. | 2018 Sep |
1 |
| 26 |
29995408 | Identification of the 4-Position of 3-Alkynyl and 3-Heteroaromatic Substituted Pyridine Methanamines as a Key Modification Site Eliciting Increased Potency and Enhanced Selectivity for Cytochrome P-450 2A6 Inhibition. | 2018 Aug 23 |
2 |
| 27 |
30087722 | Genetic Polymorphism of CYP2A6 and Its Relationship with Nicotine Metabolism in Male Bataknese Smokers Suffered from Lung Cancer in Indonesia. | 2018 Jul 20 |
3 |
| 28 |
27815364 | Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. | 2017 Jan |
4 |
| 29 |
27865452 | CYP2A6 Genetic Variation Alters Striatal-Cingulate Circuits, Network Hubs, and Executive Processing in Smokers. | 2017 Apr 1 |
4 |
| 30 |
27974382 | Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities. | 2017 Mar |
6 |
| 31 |
28181923 | Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer. | 2017 May |
1 |
| 32 |
28298240 | Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver. | 2017 Mar 15 |
1 |
| 33 |
28432340 | Phenome-wide association study for CYP2A6 alleles: rs113288603 is associated with hearing loss symptoms in elderly smokers. | 2017 Apr 21 |
1 |
| 34 |
28542511 | Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study. | 2017 |
4 |
| 35 |
28556459 | Does coffee consumption impact on heaviness of smoking? | 2017 Oct |
1 |
| 36 |
28583088 | Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues. | 2017 Jun 5 |
1 |
| 37 |
28734893 | Genetic polymorphisms in CYP2A6 are associated with a risk of cigarette smoking and predispose to smoking at younger ages. | 2017 Sep 10 |
2 |
| 38 |
28856944 | Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea. | 2017 Dec |
1 |
| 39 |
29048184 | Association of nicotine metabolism and sex with relapse following varenicline and nicotine replacement therapy. | 2017 Oct |
2 |
| 40 |
25744963 | CYP2A6 Longitudinal Effects in Young Smokers. | 2016 Feb |
3 |
| 41 |
26069034 | The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio. | 2016 Apr |
1 |
| 42 |
26541911 | CYP2A6 Effects on Subjective Reactions to Initial Smoking Attempt. | 2016 May |
4 |
| 43 |
26648056 | Common and Distinct Interactions of Chemical Inhibitors with Cytochrome P450 CYP1A2, CYP2A6 and CYP2B6 Enzymes. | 2016 |
1 |
| 44 |
26818358 | Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity. | 2016 Mar |
2 |
| 45 |
26851241 | Inactivation of CYP2A6 by the Dietary Phenylpropanoid trans-Cinnamic Aldehyde (Cinnamaldehyde) and Estimation of Interactions with Nicotine and Letrozole. | 2016 Apr |
1 |
| 46 |
27035242 | Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity. | 2016 Jul |
3 |
| 47 |
27338962 | Genetics of Substance Use Disorders. | 2016 Jul |
1 |
| 48 |
27488534 | Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk. | 2016 Oct 1 |
4 |
| 49 |
27599351 | Application of a pharmacokinetic/pharmacogenetic approach to assess the nicotine metabolic profile of smokers in the real-life setting. | 2016 Nov 30 |
2 |
| 50 |
28101244 | Celery extract inhibits mouse CYP2A5 and human CYP2A6 activities via different mechanisms. | 2016 Dec |
1 |