gemcitabine

ribonucleotide reductase catalytic subunit M1 ; Homo sapiens







133 Article(s)
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51 24772321 Expression of ribonucleoside reductase subunit M1, but not excision repair cross-complementation group 1, is predictive in muscle-invasive bladder cancer treated with chemotherapy and radiation. 2014 May 2
52 25227833 Expression of ERCC1, RRM1 and LRP in non-small cell lung cancers and their influence on chemotherapeutic efficacy of gemcitabine concomitant with nedaplatin. 2014 1
53 25327655 [Relationship between the efficacy of gemcitabine/cisplatin adjuvant chemotherapy and RRM1 protein expression in postoperative NSCLC patients]. 2014 Jul 4
54 25664003 Gemcitabine sensitivity factors, hENT1 and RRM1 as potential prognostic biomarker for advanced biliary tract cancer. 2014 3
55 22736490 Predictive and prognostic roles of ribonucleotide reductase M1 in resectable pancreatic adenocarcinoma. 2013 Jan 1 2
56 23253379 Combined analysis of intratumoral human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression is a powerful predictor of survival in patients with pancreatic carcinoma treated with adjuvant gemcitabine-based chemotherapy after operative resection. 2013 Apr 3
57 23261218 The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression. 2013 Mar 2
58 23483975 A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy. 2013 8
59 23570983 Just getting into cells is not enough: mechanisms underlying 4-(N)-stearoyl gemcitabine solid lipid nanoparticle's ability to overcome gemcitabine resistance caused by RRM1 overexpression. 2013 Jul 10 2
60 23710668 Prognostic predictive values of gemcitabine sensitivity-related gene products for unresectable or recurrent biliary tract cancer treated with gemcitabine alone. 2013 May 27 3
61 23905902 Do hENT1 and RRM1 predict the clinical benefit of gemcitabine in pancreatic cancer? 2013 Aug 1
62 23982437 Predictive value of ERCC1 and RRM1 gene single-nucleotide polymorphisms for first-line platinum- and gemcitabine-based chemotherapy in non-small cell lung cancer patients. 2013 Nov 2
63 23991987 Predictive and prognostic roles of ribonucleotide reductase M1 in patients with pancreatic cancer treated with gemcitabine: a meta-analysis. 2013 6
64 24045016 Phase II trial of customized first line chemotherapy according to ERCC1 and RRM1 SNPs in patients with advanced non-small-cell lung cancer. 2013 Nov 2
65 24215511 Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine. 2013 Nov 12 3
66 24595080 The tailored chemotherapy based on RRM1 immunohistochemical expression in patients with advanced non-small cell lung cancer. 2013 Jan 1 2
67 25806229 Predictive models for customizing chemotherapy in advanced non-small cell lung cancer (NSCLC). 2013 Jun 2
68 21889227 RRM1 expression and clinical outcome of gemcitabine-containing chemotherapy for advanced non-small-cell lung cancer: a meta-analysis. 2012 Mar 6
69 22028294 Preliminary indication of survival benefit from ERCC1 and RRM1-tailored chemotherapy in patients with advanced nonsmall cell lung cancer: evidence from an individual patient analysis. 2012 May 1 2
70 22134350 The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma. 2012 Jan 1
71 22173087 Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer. 2012 Feb 1
72 22302408 RRM1 and ERCC1 expression in peripheral blood versus tumor tissue in gemcitabine/carboplatin-treated advanced non-small cell lung cancer. 2012 May 2
73 22330686 The potential of exploiting DNA-repair defects for optimizing lung cancer treatment. 2012 Feb 14 1
74 22425885 Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles. 2012 Jun 15 2
75 22692073 Expression of RRM1 and its association with resistancy to gemcitabine-based chemotherapy in advanced nasopharyngeal carcinoma. 2012 Oct 5
76 22705007 Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma. 2012 Sep 1
77 23086647 [Expression of RRM1 and ERCC1 genes in tumor tissues and peripheral blood lymphocytes of advanced non-small cell lung cancer]. 2012 Sep 1
78 23359225 Individualized Chemotherapy in Advanced NSCLC Patients Based on mRNA Levels of BRCA1 and RRM1. 2012 Sep 2
79 28920258 Response to gemcitabine-platinum chemotherapy by single nucleotide polymorphisms of RRM1 and ERCC1 genes in patients with non-small-cell lung cancer. 2012 Feb 2
80 20467918 ERCC1, RRM1 and BRCA1 mRNA expression levels and clinical outcome of advanced non-small cell lung cancer. 2011 Dec 1
81 21163702 The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer. 2011 Jul 1
82 21220199 Association of RRM1 -37A>C polymorphism with clinical outcome in colorectal cancer patients treated with gemcitabine-based chemotherapy. 2011 Apr 2
83 21264830 DNA repair gene polymorphisms and benefit from gefitinib in never-smokers with lung adenocarcinoma. 2011 Jul 15 1
84 21264835 Prognostic roles of human equilibrative transporter 1 (hENT-1) and ribonucleoside reductase subunit M1 (RRM1) in resected pancreatic cancer. 2011 Jul 15 1
85 21370501 RRM1 gene expression in peripheral blood is predictive of shorter survival in Chinese patients with advanced non-small-cell lung cancer treated by gemcitabine and platinum. 2011 Mar 4
86 21496433 [Relations between RRM1 protein expression levels and effects of gemcitabine and cisplatin chemotherapy in advanced non-small cell lung cancer patients]. 2011 Apr 4
87 21529991 Synergistic cytotoxicity, inhibition of signal transduction pathways and pharmacogenetics of sorafenib and gemcitabine in human NSCLC cell lines. 2011 Nov 1
88 21617862 Predicting the chemosensitivity of pancreatic cancer cells by quantifying the expression levels of genes associated with the metabolism of gemcitabine and 5-fluorouracil. 2011 Aug 2
89 21642870 Differential effect of polymorphisms of CMPK1 and RRM1 on survival in advanced non-small cell lung cancer patients treated with gemcitabine or taxane/cisplatinum. 2011 Aug 3
90 21645463 [Gemcitabine in RRM1-negative advanced refractory non-small cell lung cancer (NSCLC): a case report]. 2011 Jun 1
91 21893046 Modulation of the ribonucleotide reductase M1-gemcitabine interaction in vivo by N-ethylmaleimide. 2011 Sep 23 8
92 21940346 Ribonucleotide reductase M1 expression in intrahepatic cholangiocarcinoma. 2011 Sep-Oct 4
93 19968494 In situ protein expression of RRM1, ERCC1, and BRCA1 in metastatic breast cancer patients treated with gemcitabine-based chemotherapy. 2010 Feb 3
94 20211060 [Expression of Gemcitabine-resistance-related gene and polymorphism of ribonucleotide reductase M1 gene promoter in Gemcitabine-resistant A549/Gem and NCI-H460/Gem cell lines]. 2010 Jan 2
95 20223551 The immunohistochemical overexpression of ribonucleotide reductase regulatory subunit M1 (RRM1) protein is a predictor of shorter survival to gemcitabine-based chemotherapy in advanced non-small cell lung cancer (NSCLC). 2010 Nov 3
96 20226083 RRM1 single nucleotide polymorphism -37C-->A correlates with progression-free survival in NSCLC patients after gemcitabine-based chemotherapy. 2010 Mar 13 6
97 20438561 Ribonucleotide reductase subunit M1 expression in resectable, muscle-invasive urothelial cancer correlates with survival in younger patients. 2010 Dec 1
98 20443070 Impact of biomarkers on non-small cell lung cancer treatment. 2010 Mar 2
99 20811706 Ribonucleotide reductase subunit M1 assessed by quantitative double-fluorescence immunohistochemistry predicts the efficacy of gemcitabine in biliary tract carcinoma. 2010 Oct 6
100 20868593 [Expression and predictive role of excision repair cross complementation group 1, ribonucleotide reductase subunit M1, and β-tubulin 3 in postoperative patients with non-small cell lung cancer receiving adjuvant chemotherapy]. 2010 Aug 1