Alitretinoin

retinoic acid receptor alpha ; Homo sapiens







26 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34303791 Human prostate epithelial cells and prostate-derived stem cells malignantly transformed in vitro with sodium arsenite show impaired Toll like receptor -3 (TLR3)-associated anti-tumor pathway. 2021 Oct 10 1
2 28223944 IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes. 2017 1
3 28746836 A human induced pluripotent stem cell-based in vitro assay predicts developmental toxicity through a retinoic acid receptor-mediated pathway for a series of related retinoid analogues. 2017 Oct 2
4 30108774 The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors. 2017 Mar 1 1
5 21489804 Replacement of the hydrophobic part of 9-cis-retinoic acid with cyclic terpenoid moiety results in RXR-selective agonistic activity. 2011 May 1 2
6 19920921 Alitretinoin--its use in intractable hand eczema and other potential indications. 2009 Sep 21 2
7 18321241 Alitretinoin: a comprehensive review. 2008 Mar 2
8 18922886 Retinoic acid-dependent activation of the polycystic kidney disease-1 (PKD1) promoter. 2008 Dec 1
9 17451432 Involvement of NF-kappaB subunit p65 and retinoic acid receptors, RARalpha and RXRalpha, in transcriptional regulation of the human GnRH II gene. 2007 Jun 1
10 16085646 Physiological and receptor-selective retinoids modulate interferon gamma signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1. 2005 Oct 28 3
11 12846418 Effect of ligands of nuclear hormone receptors on sodium/iodide symporter expression and activity in breast cancer cells. 2003 Jun 3
12 11945128 Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid. 2002 Mar 1
13 11212249 Increased retinoic acid responsiveness in lung carcinoma cells that are nonresponsive despite the presence of endogenous retinoic acid receptor (RAR) beta by expression of exogenous retinoid receptors retinoid X receptor alpha, RAR alpha, and RAR gamma. 2001 Jan 15 1
14 10778990 Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells. 2000 Apr 1
15 11142476 A phase I-II study of 9-cis retinoic acid and interferon-alpha2b in patients with advanced renal-cell carcinoma: an NCIC Clinical Trials Group study. 2000 Nov 1
16 9506453 Retinoic acid receptor-gamma in human epidermis preferentially traps all-trans retinoic acid as its ligand rather than 9-cis retinoic acid. 1998 Mar 1
17 9083083 Retinoic acid receptor/retinoid X receptor heterodimers can be activated through both subunits providing a basis for synergistic transactivation and cellular differentiation. 1997 Apr 4 1
18 9205071 Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status. 1997 Jul 1 2
19 9218465 Mutational analysis reveals that all-trans-retinoic acid, 9-cis-retinoic acid, and antagonist interact with distinct binding determinants of RARalpha. 1997 Jul 18 1
20 8620004 Individual subunits of heterodimers comprised of retinoic acid and retinoid X receptors interact with their ligands independently. 1996 Mar 26 2
21 8765055 Derivation and characterization of retinoid-resistant human embryonal carcinoma cells. 1996 Jul 1
22 8947586 Mutation in the ligand-binding domain of the retinoic acid receptor alpha in HL-60 leukemic cells resistant to retinoic acid and with increased sensitivity to vitamin D3 analogs. 1996 Sep 1
23 7657595 Mutagenesis of the ligand binding domain of the human retinoic acid receptor alpha identifies critical residues for 9-cis-retinoic acid binding. 1995 Sep 1 4
24 7852380 Endogenous retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR beta 2/RARE (DR5). 1995 Feb 17 2
25 8158845 [Effects of 9-cis retinoic acid on hematopoiesis in vitro]. 1994 Mar 1
26 8260698 Effects of novel retinoic acid compound, 9-cis-retinoic acid, on proliferation, differentiation, and expression of retinoic acid receptor-alpha and retinoid X receptor-alpha RNA by HL-60 cells. 1993 Dec 15 2