| 1 |
34037423 | An Amino Acid Polymorphism within the HIV-1 Nef Dileucine Motif Functionally Uncouples Cell Surface CD4 and SERINC5 Downregulation. | 2021 Jul 26 |
7 |
| 2 |
34358561 | The HIV-1 accessory protein Nef increases surface expression of the checkpoint receptor Tim-3 in infected CD4+ T cells. | 2021 Sep |
5 |
| 3 |
30053425 | HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. | 2018 Jul 26 |
2 |
| 4 |
23151229 | Identification of a novel binding site between HIV type 1 Nef C-terminal flexible loop and AP2 required for Nef-mediated CD4 downregulation. | 2013 Apr |
6 |
| 5 |
21477083 | Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly. | 2011 Jul |
1 |
| 6 |
21543478 | HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elements. | 2011 Jul |
1 |
| 7 |
19129443 | A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex. | 2009 Mar |
1 |
| 8 |
18032517 | A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2. | 2008 Feb |
3 |
| 9 |
18073204 | The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail. | 2008 Feb 8 |
2 |
| 10 |
18524831 | Competition model for upregulation of the major histocompatibility complex class II-associated invariant chain by human immunodeficiency virus type 1 Nef. | 2008 Aug |
2 |
| 11 |
18596106 | Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain. | 2008 Sep |
1 |
| 12 |
17267500 | Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. | 2007 Apr |
1 |
| 13 |
15956605 | Detection of human immunodeficiency virus type 1 Nef and CD4 physical interaction in living human cells by using bioluminescence resonance energy transfer. | 2005 Jul |
1 |
| 14 |
16116206 | HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent. | 2005 Sep 1 |
2 |
| 15 |
10814565 | Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif. | 2000 May 25 |
2 |
| 16 |
11000208 | Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine LIGHT on activated T cells. | 2000 Oct |
2 |
| 17 |
10366557 | The dileucine-based sorting motif in HIV-1 Nef is not required for down-regulation of class I MHC. | 1999 Jun 5 |
1 |
| 18 |
9736718 | Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. | 1998 Sep 15 |
5 |
| 19 |
9811606 | A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. | 1998 Nov 5 |
1 |
| 20 |
9811611 | A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. | 1998 Nov 5 |
2 |
| 21 |
9314527 | Nef-mediated clathrin-coated pit formation. | 1997 Oct 6 |
1 |