| 1 |
35445401 | Valosin-containing protein regulates the stability of fused in sarcoma granules in cells by changing ATP concentrations. | 2022 Jun |
2 |
| 2 |
33456290 | Anti-HCMV activity by an irreversible p97 inhibitor LC-1310. | 2021 Jan 9 |
2 |
| 3 |
33476933 | A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells. | 2021 Mar 5 |
1 |
| 4 |
33911929 | Structural insight into mutations at 155 position of valosin containing protein (VCP) linked to inclusion body myopathy with Paget disease of bone and frontotemporal Dementia. | 2021 Apr |
1 |
| 5 |
33941661 | A Role for VCP/p97 in the Processing of Drug-Stabilized TOP2-DNA Covalent Complexes. | 2021 Jul |
2 |
| 6 |
32162487 | Allosteric p97 Inhibitors Can Overcome Resistance to ATP-Competitive p97 Inhibitors for Potential Anticancer Therapy. | 2020 Apr 20 |
8 |
| 7 |
32790300 | Observation of a Transient Reaction Intermediate Illuminates the Mechanochemical Cycle of the AAA-ATPase p97. | 2020 Aug 26 |
1 |
| 8 |
32961852 | Mitochondrial Surveillance by Cdc48/p97: MAD vs. Membrane Fusion. | 2020 Sep 18 |
1 |
| 9 |
33028677 | An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase. | 2020 Oct 20 |
1 |
| 10 |
31368616 | Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib-sensitive and -resistant multiple myeloma cells. | 2019 Oct |
2 |
| 11 |
28360103 | Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons. | 2017 May 26 |
5 |
| 12 |
28512218 | Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy. | 2017 May 30 |
2 |
| 13 |
28939772 | Interaction between the AAA+ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding. | 2017 Nov 10 |
1 |
| 14 |
27105284 | p97 Composition Changes Caused by Allosteric Inhibition Are Suppressed by an On-Target Mechanism that Increases the Enzyme's ATPase Activity. | 2016 Apr 21 |
1 |
| 15 |
27267671 | p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions. | 2016 Aug 19 |
3 |
| 16 |
27503804 | Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration. | 2016 Aug 9 |
3 |
| 17 |
27716483 | VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair. | 2016 Oct 6 |
1 |
| 18 |
25724235 | In vitro studies in VCP-associated multisystem proteinopathy suggest altered mitochondrial bioenergetics. | 2015 May |
2 |
| 19 |
25775548 | Altered cofactor regulation with disease-associated p97/VCP mutations. | 2015 Apr 7 |
2 |
| 20 |
26389662 | Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. | 2015 Oct |
2 |
| 21 |
24885147 | VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase. | 2014 May 29 |
2 |
| 22 |
23498975 | Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels. | 2013 Apr 10 |
2 |
| 23 |
23793018 | Perturbations to the ubiquitin conjugate proteome in yeast δubx mutants identify Ubx2 as a regulator of membrane lipid composition. | 2013 Oct |
2 |
| 24 |
24055316 | High-speed atomic force microscopic observation of ATP-dependent rotation of the AAA+ chaperone p97. | 2013 Nov 5 |
1 |
| 25 |
21945179 | The Cdc48 machine in endoplasmic reticulum associated protein degradation. | 2012 Jan |
2 |
| 26 |
22298039 | Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system. | 2012 Feb 2 |
2 |
| 27 |
22945555 | Real-time determination of the activity of ATPase by use of a water-soluble polythiophene. | 2012 Nov |
2 |
| 28 |
22948820 | Lysine methylation of VCP by a member of a novel human protein methyltransferase family. | 2012 |
4 |
| 29 |
23226521 | ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain. | 2012 |
7 |
| 30 |
21249466 | Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration. | 2011 Jun |
1 |
| 31 |
20097236 | Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP. | 2010 Mar |
1 |
| 32 |
20130684 | ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97. | 2010 Feb |
2 |
| 33 |
20427671 | Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation. | 2010 Apr 28 |
1 |
| 34 |
21433362 | Probe Report for P97/cdc48 Inhibitors | 2010 |
2 |
| 35 |
19506019 | Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation. | 2009 Aug |
4 |
| 36 |
19826004 | COP9 signalosome interacts ATP-dependently with p97/valosin-containing protein (VCP) and controls the ubiquitination status of proteins bound to p97/VCP. | 2009 Dec 11 |
8 |
| 37 |
17942349 | Ubiquitin receptors and ERAD: a network of pathways to the proteasome. | 2007 Dec |
1 |
| 38 |
18044963 | Characterization of the aggregation-prevention activity of p97/valosin-containing protein. | 2007 Dec 25 |
2 |
| 39 |
16601695 | Conformational changes in the AAA ATPase p97-p47 adaptor complex. | 2006 May 3 |
1 |
| 40 |
15698563 | Conformational changes of p97 during nucleotide hydrolysis determined by small-angle X-Ray scattering. | 2005 Feb |
1 |
| 41 |
15740751 | Nucleotide dependent motion and mechanism of action of p97/VCP. | 2005 Mar 25 |
2 |
| 42 |
15037256 | Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion. | 2004 Apr-May |
2 |
| 43 |
12446676 | ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity. | 2003 Feb 7 |
1 |
| 44 |
12504076 | Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities. | 2003 Jan 10 |
2 |
| 45 |
12747802 | ATP-binding sites in brain p97/VCP (valosin-containing protein), a multifunctional AAA ATPase. | 2003 Sep 1 |
7 |
| 46 |
12807884 | D1 ring is stable and nucleotide-independent, whereas D2 ring undergoes major conformational changes during the ATPase cycle of p97-VCP. | 2003 Aug 29 |
2 |
| 47 |
11598795 | VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration. | 2001 Oct |
1 |
| 48 |
10715114 | Specificity of Ca2+-dependent protein interactions mediated by the C2A domains of synaptotagmins. | 2000 Mar 21 |
1 |
| 49 |
1382975 | VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation. | 1992 Oct |
1 |