| 1 |
34103518 | Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex. | 2021 Jun 8 |
2 |
| 2 |
34959888 | Cytotoxic Lactalbumin-Oleic Acid Complexes in the Human Milk Diet of Preterm Infants. | 2021 Nov 30 |
6 |
| 3 |
32389653 | The self-assembled α-lactalbumin-oleic acid complex inhibits ATP supply from both glycolysis and the TCA cycle in HepG2 cells and HepG2-bearing nude mice. | 2020 Sep 15 |
2 |
| 4 |
30706714 | Temperature, pH, and Molecular Packing Effects on the Penetration of Oleic Acid Monolayer by α-Lactalbumin. | 2019 Feb 26 |
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| 5 |
31082436 | Beta-sheet-specific interactions with heat shock proteins define a mechanism of delayed tumor cell death in response to HAMLET. | 2019 Jun 28 |
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| 6 |
31582209 | Effect of alpha-lactalbumin and lactoferrin oleic acid complexes on chromatin structural organization. | 2019 Nov 26 |
2 |
| 7 |
31694917 | The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in Streptococcus pneumoniae. | 2019 Dec 20 |
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| 8 |
29691701 | The Use of Human, Bovine, and Camel Milk Albumins in Anticancer Complexes with Oleic Acid. | 2018 Jun |
2 |
| 9 |
27986631 | Internalization properties of the anti-tumor α-lactalbumin-oleic acid complex. | 2017 Mar |
4 |
| 10 |
28341551 | Augmenting the cytotoxicity of oleic acid-protein complexes: Potential of target-specific antibodies. | 2017 Jun |
4 |
| 11 |
28385217 | Undec-10-enoic acid functionalized chitosan based novel nano-conjugate: An enhanced anti-bacterial/biofilm and anti-cancer potential. | 2017 Jun 15 |
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| 12 |
28549296 | Formation mechanism of α-lactalabumin/oleic acid complex characterized by 2D correlation analysis. | 2017 Oct 5 |
2 |
| 13 |
28949782 | Divergent Anticancer Activity of Free and Formulated Camel Milk α-Lactalbumin. | 2017 Oct 21 |
4 |
| 14 |
29123177 | Liprotides kill cancer cells by disrupting the plasma membrane. | 2017 Nov 9 |
4 |
| 15 |
26916155 | Disorder in Milk Proteins: α-Lactalbumin. Part B. A Multifunctional Whey Protein Acting as an Oligomeric Molten Globular "Oil Container" in the Anti-Tumorigenic Drugs, Liprotides. | 2016 Jul 15 |
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| 16 |
27068540 | Liprotides made of α-lactalbumin and cis fatty acids form core-shell and multi-layer structures with a common membrane-targeting mechanism. | 2016 Jul |
4 |
| 17 |
27109252 | Behaviour of oleic acid-depleted bovine alpha-lactalbumin made LEthal to tumor cells (BAMLET). | 2016 May 24 |
2 |
| 18 |
27424089 | Oleic acid-embedded nanoliposome as a selective tumoricidal agent. | 2016 Oct 1 |
2 |
| 19 |
25913522 | Oleic acid complex of bovine α-lactalbumin induces eryptosis in human and other erythrocytes by a Ca(2+)-independent mechanism. | 2015 Sep |
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| 20 |
26297199 | α-Lactalbumin:Oleic Acid Complex Spontaneously Delivers Oleic Acid to Artificial and Erythrocyte Membranes. | 2015 Sep 25 |
2 |
| 21 |
24139905 | The effect of proteolysis on the induction of cell death by monomeric alpha-lactalbumin. | 2014 Feb |
1 |
| 22 |
24368211 | Bovine lactoferrin binds oleic acid to form an anti-tumor complex similar to HAMLET. | 2014 Apr 4 |
2 |
| 23 |
25310453 | A microscopic insight from conformational thermodynamics to functional ligand binding in proteins. | 2014 Dec |
5 |
| 24 |
25403886 | Generic structures of cytotoxic liprotides: nano-sized complexes with oleic acid cores and shells of disordered proteins. | 2014 Dec 15 |
1 |
| 25 |
22777854 | Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications. | 2013 Jan |
3 |
| 26 |
23441831 | Protein-fatty acid complexes: biochemistry, biophysics and function. | 2013 Apr |
2 |
| 27 |
23499846 | The biological activities of protein/oleic acid complexes reside in the fatty acid. | 2013 Jun |
4 |
| 28 |
23580643 | Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes. | 2013 May 17 |
2 |
| 29 |
23629662 | Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death. | 2013 Jun 14 |
3 |
| 30 |
23947814 | Structural characterization of more potent alternatives to HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid. | 2013 Sep 10 |
2 |
| 31 |
24039698 | Oleic acid may be the key contributor in the BAMLET-induced erythrocyte hemolysis and tumoricidal action. | 2013 |
1 |
| 32 |
23130929 | HAMLET: functional properties and therapeutic potential. | 2012 Oct |
1 |
| 33 |
23300861 | Low resolution solution structure of HAMLET and the importance of its alpha-domains in tumoricidal activity. | 2012 |
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| 34 |
21457462 | The toxicity of bovine α-lactalbumin made lethal to tumor cells is highly dependent on oleic acid and induces killing in cancer cell lines and noncancer-derived primary cells. | 2011 Jun |
3 |
| 35 |
21524506 | Preparation and comparison of cytotoxic complexes formed between oleic acid and either bovine or human α-lactalbumin. | 2011 May |
3 |
| 36 |
19968717 | The oleic acid complexes of proteolytic fragments of alpha-lactalbumin display apoptotic activity. | 2010 Jan |
1 |
| 37 |
20053771 | BAMLET activates a lysosomal cell death program in cancer cells. | 2010 Jan |
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| 38 |
20186341 | HAMLET interacts with lipid membranes and perturbs their structure and integrity. | 2010 Feb 23 |
2 |
| 39 |
20232795 | Effect of denaturation of alpha-lactalbumin on the formation of BAMLET (bovine alpha-lactalbumin made lethal to tumor cells). | 2010 Apr 14 |
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| 40 |
20804154 | α-Lactalbumin forms with oleic acid a high molecular weight complex displaying cytotoxic activity. | 2010 Oct 5 |
5 |
| 41 |
20977665 | Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes. | 2010 Nov |
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| 42 |
18985467 | Can misfolded proteins be beneficial? The HAMLET case. | 2009 |
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| 43 |
19048621 | HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death. | 2009 Mar 1 |
1 |
| 44 |
19588235 | Interaction of antitumor alpha-lactalbumin-oleic acid complexes with artificial and natural membranes. | 2009 Jun |
3 |
| 45 |
19766653 | alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding. | 2009 Dec 18 |
2 |
| 46 |
18774773 | Heat-treatment method for producing fatty acid-bound alpha-lactalbumin that induces tumor cell death. | 2008 Nov 7 |
3 |
| 47 |
19006329 | Who is Mr. HAMLET? Interaction of human alpha-lactalbumin with monomeric oleic acid. | 2008 Dec 9 |
2 |
| 48 |
16678133 | alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death. | 2006 Jun 23 |
2 |
| 49 |
15659367 | Stability of HAMLET--a kinetically trapped alpha-lactalbumin oleic acid complex. | 2005 Feb |
2 |
| 50 |
15822935 | Conversion of human alpha-lactalbumin to an apo-like state in the complexes with basic poly-amino acids: toward understanding of the molecular mechanism of antitumor action of HAMLET. | 2005 Mar-Apr |
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