pyrazolanthrone

TTK protein kinase ; Homo sapiens







6 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 24462521 TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers. 2014 May 1
2 23634759 Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125). 2013 Jun 13 2
3 22438244 Selective killing of p53-deficient cancer cells by SP600125. 2012 Jun 3
4 20099905 Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes. 2010 Mar 2 3
5 18480048 Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125. 2008 Aug 1 3
6 16113653 Ablation of the spindle assembly checkpoint by a compound targeting Mps1. 2005 Sep 4