Protein Name ribosomal protein S6 kinase B1
Organism Rattus norvegicus
Gene ID 83840
Gene Symbol

Rps6kb1

UniProt P67999 (KS6B1_RAT)
Relationships Total Number of functionally related compound(s) : 301
Total Number of Articles : 412
Description

ribosomal protein S6 kinase B1

Gene Summary

Enables several functions, including ATP binding activity; PDZ domain binding activity; and protein phosphatase 2A binding activity. Involved in several processes, including long-term memory; positive regulation of skeletal muscle tissue growth; and skeletal muscle atrophy. Located in cell surface and perinuclear region of cytoplasm. Is active in postsynapse. Biomarker of several diseases, including autosomal dominant polycystic kidney disease; hyperinsulinism; muscular atrophy; obesity; and primary biliary cholangitis. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • ribosomal protein S6 kinase beta-1
  • 70 kDa ribosomal protein S6 kinase 1
  • P70S6K
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Properties