| Protein Name | cytochrome P450, family 3, subfamily a, polypeptide 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 266682 |
| Gene Symbol | Cyp3a2 |
| UniProt | P05183 (CP3A2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
255
Total Number of Articles : 254 |
Description |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
| Gene Summary |
Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in oxidative demethylation and xenobiotic metabolic process. Predicted to be located in cytoplasm. Used to study alcohol dependence and anxiety disorder. Biomarker of cholestasis and end stage renal disease. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A5 (cytochrome P450 family 3 subfamily A member 5). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |