Protein Name dipeptidyl peptidase 8
Organism Homo sapiens
Gene ID 54878
Gene Symbol

DPP8

UniProt Q6V1X1 (DPP8_HUMAN), A0A024R5Z6 (A0A024R5Z6_HUMAN), A8K4U2 (A8K4U2_HUMAN), B4DLA8 (B4DLA8_HUMAN)
Relationships Total Number of functionally related compound(s) : 82
Total Number of Articles : 68
Description

dipeptidyl peptidase 8

Gene Summary

This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

synonyms
  • dipeptidyl peptidase 8
  • DPP VIII
  • dipeptidyl peptidase IV-related protein 1
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Properties