Protein Name | fibroblast growth factor 2 |
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Organism | Mus musculus |
Gene ID | 14173 |
Gene Symbol | Fgf2 |
UniProt | P15655 (FGF2_MOUSE), Q541T2 (Q541T2_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
611
Total Number of Articles : 767 |
Description |
fibroblast growth factor 2 |
Gene Summary |
Enables growth factor activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of protein phosphorylation; and stem cell development. Acts upstream of or within several processes, including nervous system development; positive regulation of cell differentiation; and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2). [provided by Alliance of Genome Resources, May 2025] |
synonyms |
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Properties | |