Protein Name fibroblast growth factor 2
Organism Mus musculus
Gene ID 14173
Gene Symbol

Fgf2

UniProt P15655 (FGF2_MOUSE), Q541T2 (Q541T2_MOUSE)
Relationships Total Number of functionally related compound(s) : 611
Total Number of Articles : 767
Description

fibroblast growth factor 2

Gene Summary

Enables growth factor activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of protein phosphorylation; and stem cell development. Acts upstream of or within several processes, including nervous system development; positive regulation of cell differentiation; and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • fibroblast growth factor 2
  • HBGF-2
  • basic fibroblast growth factor
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Properties