Protein Name BH3 interacting domain death agonist
Organism Mus musculus
Gene ID 12122
Gene Symbol

Bid

UniProt P70444 (BID_MOUSE)
Relationships Total Number of functionally related compound(s) : 167
Total Number of Articles : 192
Description

BH3 interacting domain death agonist

Gene Summary

Enables ubiquitin protein ligase binding activity. Involved in positive regulation of cellular component organization; protein-containing complex assembly; and release of cytochrome c from mitochondria. Acts upstream of or within several processes, including apoptotic signaling pathway; hepatocyte apoptotic process; and regulation of apoptotic process. Located in cytosol and mitochondrial membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and limb segment. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human BID (BH3 interacting domain death agonist). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • BH3-interacting domain death agonist
  • p22 BID
  • 2700049M22Rik
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Properties