| Protein Name | cytochrome P450, family 24, subfamily a, polypeptide 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13081 |
| Gene Symbol | Cyp24a1 |
| UniProt | Q64441 (CP24A_MOUSE), Q3TWW0 (Q3TWW0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
79
Total Number of Articles : 97 |
Description |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
| Gene Summary |
The protein encoded by this gene localizes to the mitochondrion, where it degrades calcitriol to calcitetrol. This gene is upregulated by binding of calcitriol to the upstream regulatory region and to a downstream enhancer region, thereby allowing calcitriol to autoregulate its concentration in the cell. The encoded protein may also play a role in calcium homeostasis. [provided by RefSeq, Aug 2015] |
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