Protein Name | AT-rich interaction domain 4B |
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Organism | Homo sapiens |
Gene ID | 51742 |
Gene Symbol | ARID4B |
UniProt | Q4LE39 (ARI4B_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
159
Total Number of Articles : 220 |
Description |
AT-rich interaction domain 4B |
Gene Summary |
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |