Protein Name AT-rich interaction domain 4B
Organism Homo sapiens
Gene ID 51742
Gene Symbol

ARID4B

UniProt Q4LE39 (ARI4B_HUMAN)
Relationships Total Number of functionally related compound(s) : 159
Total Number of Articles : 220
Description

AT-rich interaction domain 4B

Gene Summary

This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

synonyms
  • AT-rich interactive domain-containing protein 4B
  • 180 kDa Sin3-associated polypeptide
  • ARID domain-containing protein 4B
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Properties