Protein Name solute carrier family 12 member 3
Organism Rattus norvegicus
Gene ID 54300
Gene Symbol

Slc12a3

UniProt P55018 (S12A3_RAT), G3V8G0 (G3V8G0_RAT)
Relationships Total Number of functionally related compound(s) : 49
Total Number of Articles : 60
Description

solute carrier family 12 member 3

Gene Summary

Enables enzyme binding activity and sodium:chloride symporter activity. Involved in chloride transport and sodium ion transmembrane transport. Located in apical plasma membrane and vesicle. Is active in plasma membrane. Human ortholog(s) of this gene implicated in Gitelman syndrome and essential hypertension. Orthologous to human SLC12A3 (solute carrier family 12 member 3). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • solute carrier family 12 member 3
  • Na-Cl symporter
  • solute carrier family 12 (sodium/chloride transporter), member 3
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Properties