Protein Name acetylcholinesterase
Organism Rattus norvegicus
Gene ID 83817
Gene Symbol

Ache

UniProt P37136 (ACES_RAT), Q505J2 (Q505J2_RAT)
Relationships Total Number of functionally related compound(s) : 1302
Total Number of Articles : 2270
Description

acetylcholinesterase

Gene Summary

Enables acetylcholine binding activity and acetylcholinesterase activity. Involved in several processes, including acetylcholine catabolic process; nervous system development; and positive regulation of neurogenesis. Located in several cellular components, including endoplasmic reticulum lumen; membrane raft; and synaptic membrane. Is active in neuromuscular junction and synaptic cleft. Biomarker of acute stress disorder and leptospirosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; drug dependence (multiple); epilepsy; myasthenia gravis; and subacute delirium. Orthologous to human ACHE (acetylcholinesterase (Yt blood group)). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • acetylcholinesterase
  • glycolipid-anchored form of acetylcholinesterase
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Properties