| Protein Name | eosinophil peroxidase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13861 |
| Gene Symbol | Epx |
| UniProt | P49290 (PERE_MOUSE), Q3V1J3 (Q3V1J3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
63
Total Number of Articles : 47 |
Description |
eosinophil peroxidase |
| Gene Summary |
This gene encodes a member of the peroxidase superfamily of enzymes that is produced by eosinophils and plays a critical role in eliminating tissue-invasive parasites. The encoded preproprotein undergoes proteolytic processing to generate a heterodimeric enzyme that forms a predominant component of the intracellular granules of eosinophils. Mice lacking the encoded protein exhibit resistance to ulcerative colitis induced by dextran sulfate. [provided by RefSeq, Jul 2016] |
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