| Protein Name | monoglyceride lipase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 11343 |
| Gene Symbol | MGLL |
| UniProt | Q99685 (MGLL_HUMAN), A0A0C4DFN3 (A0A0C4DFN3_HUMAN), E7EWX8 (E7EWX8_HUMAN), B2ZGL7 (B2ZGL7_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
283
Total Number of Articles : 311 |
Description |
monoglyceride lipase |
| Gene Summary |
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] |
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| Properties | |