Protein Name versican
Organism Homo sapiens
Gene ID 1462
Gene Symbol

VCAN

UniProt P13611 (CSPG2_HUMAN), A0A024RAP3 (A0A024RAP3_HUMAN), A0A024RAL1 (A0A024RAL1_HUMAN), A0A024RAQ9 (A0A024RAQ9_HUMAN), Q86W61 (Q86W61_HUMAN), Q59FG9 (Q59FG9_HUMAN), Q6MZK8 (Q6MZK8_HUMAN)
Relationships Total Number of functionally related compound(s) : 99
Total Number of Articles : 145
Description

versican

Gene Summary

This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

synonyms
  • versican core protein
  • chondroitin sulfate proteoglycan core protein 2
  • glial hyaluronate-binding protein
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Properties