Protein Name placental growth factor
Organism Rattus norvegicus
Gene ID 94203
Gene Symbol

Pgf

UniProt Q63434 (PLGF_RAT)
Relationships Total Number of functionally related compound(s) : 106
Total Number of Articles : 74
Description

placental growth factor

Gene Summary

Enables identical protein binding activity. Involved in several processes, including positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; and sprouting angiogenesis. Located in extracellular space. Used to study congestive heart failure and myocardial infarction. Biomarker of diabetic retinopathy; end stage renal disease; pre-eclampsia; and status epilepticus. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • placenta growth factor
  • Plgf
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Properties