Protein Name ADRM1 26S proteasome ubiquitin receptor
Organism Homo sapiens
Gene ID 11047
Gene Symbol

ADRM1

UniProt Q16186 (ADRM1_HUMAN), A0A087WX59 (A0A087WX59_HUMAN)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 44
Description

ADRM1 26S proteasome ubiquitin receptor

Gene Summary

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

synonyms
  • proteasomal ubiquitin receptor ADRM1
  • 110 kDa cell membrane glycoprotein
  • M(r) 110,000 surface antigen
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Properties