Protein Name indoleamine 2,3-dioxygenase 1
Organism Mus musculus
Gene ID 15930
Gene Symbol

Ido1

UniProt P28776 (I23O1_MOUSE), D3YXV1 (D3YXV1_MOUSE)
Relationships Total Number of functionally related compound(s) : 292
Total Number of Articles : 531
Description

indoleamine 2,3-dioxygenase 1

Gene Summary

Enables tryptophan 2,3-dioxygenase activity. Involved in quinolinate biosynthetic process. Acts upstream of or within several processes, including carboxylic acid metabolic process; regulation of apoptotic process; and regulation of cytokine production. Located in smooth muscle contractile fiber and stereocilium bundle. Is expressed in cerebral cortex; corpus striatum; embryo; extraembryonic component; and hippocampus. Used to study pre-eclampsia. Orthologous to human IDO1 (indoleamine 2,3-dioxygenase 1). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • indoleamine 2,3-dioxygenase 1
  • IDO-1
  • indole 2,3-dioxygenase
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Properties