| Protein Name | SET domain bifurcated histone lysine methyltransferase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 9869 |
| Gene Symbol | SETDB1 |
| UniProt | Q15047 (SETB1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
42
Total Number of Articles : 66 |
Description |
SET domain bifurcated histone lysine methyltransferase 1 |
| Gene Summary |
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011] |
| synonyms |
|
| Properties | |