| Protein Name | Superoxide dismutase 1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 39251 |
| Gene Symbol | Sod1 |
| UniProt | P61851 (SODC_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
84
Total Number of Articles : 102 |
Description |
Superoxide dismutase 1 |
| Gene Summary |
Enables protein homodimerization activity and superoxide dismutase activity. Involved in several processes, including determination of adult lifespan; positive regulation of mitophagy; and regulation of synaptic plasticity. Located in peroxisome. Is expressed in several structures, including Malpighian tubule; digestive system; germline cell; gonad; and salivary gland. Used to study amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 1. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |