| Protein Name | nuclear receptor subfamily 3, group C, member 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24413 |
| Gene Symbol | Nr3c1 |
| UniProt | P06536 (GCR_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
530
Total Number of Articles : 1157 |
Description |
nuclear receptor subfamily 3, group C, member 1 |
| Gene Summary |
Enables several functions, including heat shock protein binding activity; receptor tyrosine kinase binding activity; and transcription coactivator activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; regulation of synaptic plasticity; and response to glucocorticoid. Located in several cellular components, including chromatin; cytosol; and dendritic spine. Part of protein-containing complex. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Used to study several diseases, including alcohol dependence; alcohol use disorder; alcoholic neuropathy; cocaine abuse; and morphine dependence. Biomarker of several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; brain disease (multiple); cocaine dependence; and cognitive disorder (multiple). Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; anorexia nervosa; heroin dependence; lung disease (multiple); and nicotine dependence. Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1). [provided by Alliance of Genome Resources, May 2025] |
| synonyms |
|
| Properties | |