Protein Name exosome component 10
Organism Homo sapiens
Gene ID 5394
Gene Symbol

EXOSC10

UniProt Q01780 (EXOSX_HUMAN)
Relationships Total Number of functionally related compound(s) : 66
Total Number of Articles : 54
Description

exosome component 10

Gene Summary

Enables 3'-5'-RNA exonuclease activity and telomerase RNA binding activity. Involved in several processes, including RNA metabolic process; negative regulation of telomere maintenance via telomerase; and regulation of telomerase RNA localization to Cajal body. Located in cytosol; euchromatin; and nuclear lumen. Part of nuclear exosome (RNase complex) and small-subunit processome. [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • exosome complex component 10
  • P100 polymyositis-scleroderma overlap syndrome-associated autoantigen
  • autoantigen PM-SCL
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Properties