| Protein Name | MCL1 apoptosis regulator, BCL2 family member |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4170 |
| Gene Symbol | MCL1 |
| UniProt | Q07820 (MCL1_HUMAN), A0A087WT64 (A0A087WT64_HUMAN), C8YZ26 (C8YZ26_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
1015
Total Number of Articles : 1995 |
Description |
MCL1 apoptosis regulator, BCL2 family member |
| Gene Summary |
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010] |
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| Properties | |