Protein Name phenylethanolamine-N-methyltransferase
Organism Rattus norvegicus
Gene ID 24661
Gene Symbol

Pnmt

UniProt P10937 (PNMT_RAT)
Relationships Total Number of functionally related compound(s) : 141
Total Number of Articles : 307
Description

phenylethanolamine-N-methyltransferase

Gene Summary

Enables phenylethanolamine N-methyltransferase activity. Involved in several processes, including adrenal gland development; catecholamine metabolic process; and cellular response to dexamethasone stimulus. Located in axon; dendrite; and perikaryon. Biomarker of hypertension and hypoglycemia. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; and multiple sclerosis. Orthologous to human PNMT (phenylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • phenylethanolamine N-methyltransferase
  • PNMTase
  • noradrenaline N-methyltransferase
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Properties