| Protein Name | Rho guanine nucleotide exchange factor 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16801 |
| Gene Symbol | Arhgef1 |
| UniProt | Q61210 (ARHG1_MOUSE), E9PUF7 (E9PUF7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
4
Total Number of Articles : 3 |
Description |
Rho guanine nucleotide exchange factor 1 |
| Gene Summary |
Predicted to enable G protein-coupled receptor binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and microtubule depolymerization. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; liver; lung; spleen; and telencephalon. Human ortholog(s) of this gene implicated in immunodeficiency 62. Orthologous to human ARHGEF1 (Rho guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, May 2025] |
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