Protein Name epoxide hydrolase 1, microsomal
Organism Mus musculus
Gene ID 13849
Gene Symbol

Ephx1

UniProt Q9D379 (HYEP_MOUSE), E9PWK1 (E9PWK1_MOUSE)
Relationships Total Number of functionally related compound(s) : 321
Total Number of Articles : 241
Description

epoxide hydrolase 1, microsomal

Gene Summary

Enables oxysterol binding activity. Acts upstream of or within hydrocarbon catabolic process. Predicted to be located in intracellular membrane-bounded organelle and membrane. Is expressed in several structures, including brain ventricle and choroid plexus; exocrine system; integumental system; nervous system; and nose. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • epoxide hydrolase 1
  • epoxide hydratase
  • microsomal epoxide hydrolase
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Properties