| Protein Name | inhibitor of growth family member 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3621 |
| Gene Symbol | ING1 |
| UniProt | Q9UK53 (ING1_HUMAN), A0A0C4DFW2 (A0A0C4DFW2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
109
Total Number of Articles : 103 |
Description |
inhibitor of growth family member 1 |
| Gene Summary |
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
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