| Protein Name | proenkephalin |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29237 |
| Gene Symbol | Penk |
| UniProt | P04094 (PENK_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
969
Total Number of Articles : 1604 |
Description |
proenkephalin |
| Gene Summary |
Predicted to enable opioid peptide activity and opioid receptor binding activity. Involved in several processes, including cellular response to cAMP; cellular response to virus; and general adaptation syndrome, behavioral process. Located in several cellular components, including cell body fiber; perikaryon; and symmetric synapse. Is active in neuronal dense core vesicle lumen and synaptic vesicle lumen. Used to study heroin dependence. Biomarker of Parkinson's disease; alcohol use disorder; dystonia; epilepsy; and spinal disease. Human ortholog(s) of this gene implicated in overactive bladder syndrome. Orthologous to human PENK (proenkephalin). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |