| Protein Name | Argonaute 2 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 39683 |
| Gene Symbol | AGO2 |
| UniProt | Q9VUQ5 (AGO2_DROME), M9PFK7 (M9PFK7_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
13
Total Number of Articles : 13 |
Description |
Argonaute 2 |
| Gene Summary |
Enables endoribonuclease activity, cleaving siRNA-paired mRNA; siRNA binding activity; and single-stranded RNA binding activity. Involved in several processes, including cellular response to virus; dosage compensation by hyperactivation of X chromosome; and regulatory ncRNA-mediated gene silencing. Located in neuronal ribonucleoprotein granule and nucleus. Part of RISC complex and RISC-loading complex. Is expressed in adult brain cell body rind and adult head. [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |