| Protein Name | CD180 molecule |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4064 |
| Gene Symbol | CD180 |
| UniProt | Q99467 (CD180_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
14
Total Number of Articles : 14 |
Description |
CD180 molecule |
| Gene Summary |
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008] |
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| Properties | |