CPRiL

Protein Name	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Organism	Homo sapiens
Gene ID	8517
Gene Symbol	IKBKG
UniProt	Q9Y6K9 (NEMO_HUMAN), A0A087X1B1 (A0A087X1B1_HUMAN)
Relationships	Total Number of functionally related compound(s) : 268 Total Number of Articles : 267
Description	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Gene Summary	This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016]
synonyms	NF-kappa-B essential modulator 14.7K (adenovirus E3 protein) interacting protein 3 I-kappa-B kinase subunit gamma NF-kappa-B essential modifier ikB kinase subunit gamma ikB kinase-associated protein 1 incontinentia pigmenti inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma inhibitor of nuclear factor kappa B kinase subunit gamma AMCBX1 EDAID1 FIP-3 FIP3 Fip3p IKK-gamma IKKAP1 IKKG IMD33 IP IP1 IP2 IPD2 NEMO SAIDX ZC2HC9 Click to show/hide the synonyms
Properties